The Department of Laboratory Medicine and Pathology at the University of Minnesota Medical School is committed to bringing leading-edge basic and applied research and innovation to patient care.
The research-intensive faculty within the department have several major focus areas including cancer, immunology, cardiovascular disease, renal disease, diabetes, and genetics. The faculty consist of tenured associate and full professors, several of which currently hold endowed chairs or professorships. They interface with University of Minnesota departments and centers such as the Center for Immunology, Masonic Cancer Center, and the Institute for Translational Neuroscience.
Brenner tumor (IHC for E-cadherin)
Polychromatic crystalline keratopathy of the cornea
Pap smear with endocervical adenocarcinoma in situ
Macrophages (in red) surrounding a growing ductal structure in the mammary gland
Lymph node with a micrometastasis from ductal carcinoma of the breast
Leydig cells (Reinke crystal)
Epithelioid trophoblastic tumor
Blue nevus of the endocervix
Staining of the epidermal growth factor Amphiregulin (in green) in the epithelial cells in a mammary ductal structure
Clinics and Surgery Center opens
The new University of Minnesota Health Clinics and Surgery Center opened Feb. 22. It houses 37 medical specialties, more than 1,200 care providers, two pharmacies and a café. Patients will experience the same innovative care from world-renowned specialists but will benefit from an enhanced environment and services including extended clinic hours, convenient scheduling, easy check-in and check-out, and stress-free parking with improved valet parking service. The photo above is the CSC Acute Care Laboratory.
Online pathology for non-MDs
LAMP 4177 (3 credits, Spring/Summer)
Non University of Minnesota students are welcome and can register through the College of Continuing Education (CCE), University of Minnesota.
Jameson to employ CRISPR/Cas genome editing in memory T-cell studies
Steve Jameson was awarded a five-year $1.25M (direct costs) R01 from NIAID, a renewal of his long-term research grant that was recently supported through an NIH MERIT award. The award supports studies in mice using novel gene expression manipulation techniques -- including the CRISPR/Cas 9 genome editing system (see Science: The CRISPR Revolution) -- to explore the factors that dictate whether memory T cells will become resident in tissues or circulate around the body in experimental mice.
In a recent paper in Nature Jameson and David Masopust of Microbiology and Immunology describe the immune system of mice raised outside the “Specific Pathogen Free” barrier facilities that are usually used to house experimental animals and suggest that such mice may constitute a better model for understanding key aspects of the adult human immune system.