News

LMP News, December 3, 2018

LMP Employee Recognition Event is this Thursday

Once a year we gather together to recognize our LMP faculty, staff and students and our UMMC laboratory staff.  The event is scheduled at The Graduate Minneapolis Hotel in the ball room from 3:30 pm to 6:30 pm.  *Note time change*

Pediatrics honors Ferrieri

Pat Ferrieri was awarded the Gold-Headed Cane at Pediatric Grand Rounds Oct 31 in the Wilf Auditorium. This award honors life-long service to children. See Ferrieri and earlier awardees in the attached photo.

Cohn will join the HHS advisory committee

Claudia Cohn will join the Advisory Committee on Blood and Tissue Safety and Availability (ACBTSA), a 31-member federal advisory committee that provides advice to the Secretary of Health and Human Services through the Assistant Secretary for Health on a range of policy issues related to blood, blood products, and tissues.

Amin featured in American Society of Cytopathology spotlight

Khalid Amin is interviewed for a member spotlight of the month feature of the American Society of Cytopathology.  You can access the interview at this link.

Murugan speaks to prostate cancer support group

Paari Murugan spoke to the U of M Prostate Cancer Support group Nov. 8 about the recent advancements in diagnosis, screening and prognostic tests for prostate cancer. He also discussed the histopathological aspects of this disease and the role histopathology plays in guiding clinical decision making.

Faculty and staff forum is scheduled for December 5

Jakub Tolar, Dean of the Medical School and UMPhysicians Board Chair, will provide an update on the MHealth Fairview partnership and key priorities for the practice and welcome new UMPhysicians CEO Badrinath Konety, MD, MBA.  The forum will be held from 7-8 am in Moos Tower 5-125.   

LMP clinical faculty meeting slides are posted on LMP Google site

The LMP clinical faculty meeting slides from Nov 7, Nov 14 and Nov 28 are now posted on the LMP faculty Google site:  https://sites.google.com/a/umn.edu/lmp/

A friendly reminder from ALRT accounting

If you take out faculty recruits or visiting speakers/lecturers for dinner keep in mind the following requirements for reimbursement required by the University: the number of University faculty/staff accompanying a visitor for a meal should be no more than four; reimbursement for meals are limited to $100/attendee including food, beverage, tax and tip (tips should not exceed 20%); itemized receipts are required for reimbursement; and reimbursement requests must be submitted within 60 days. 

Residents can apply for funding

Residents can apply for research funding of up to $2,500; due date for proposals is January 1.  Proposals will be reviewed by a faculty committee.  More information on the application process is located here:  https://www.pathology.umn.edu/residency-fellowships/residency/research-experience

Take notice of upcoming grant application deadlines

AHC Seed Grant Applications
https://www.health.umn.edu/research/funding-opportunities/ahc-seed-grant-program

Medical School Research and Equipment Grant Applications
https://www.med.umn.edu/about/honors-awards/services-faculty-students/research-equipment-grants

Faculty publish

Hillier SL, Ferrieri P, Edwards MS, Ewell M, Ferris D, Fine P, Carey V, Meyn L, Hoagland D, Kasper DL, Paoletti LC, Hill H, Baker CJA phase II randomized, control trial of group B streptococcus (GBS) type III capsular polysaccharide -tetanus toxoid (GBS III-TT) vaccine to prevent vaginal colonization with GBS III.  Clin Infect Dis. 2018 Oct 3. doi: 10.1093/cid/ciy838. [Epub ahead of print]

Kline SE, Neaton JD, Lynfield R, Ferrieri P, Kulasingam S, Dittes K, Glennen A, Jawahir S, Kaizer A, Menk J, Johnson JR. Randomized controlled trial of a self-administered five-day antiseptic bundle versus usual disinfectant soap showers for preoperative eradication of Staphylococcus aureus colonization. Infect Control Hosp Epidemiol. 2018 Sep;39(9):1049-1057. doi: 10.1017/ice.2018.151. Epub 2018 Jul 24.

Salmasi A, Said J, Shindel AW, Khoshnoodi P, Felker ER, Sisk AE, Grogan T, McCullough D, Bennett J, Bailey H, Lawrence HJ, Elashoff DA, Marks LS, Raman SS, Febbo PG, Reiter RE. A 17-gene Genomic Prostate Score assay provides independent information on adverse pathology in the setting of combined mpMRI fusion-targeted and systematic prostate biopsy. The Journal of Urology. 2018. doi:10.1016/j.juro.2018.03.004. 

Rosenberg JE, Albersheim JA, Sathianathen NJ, Murugan P, Weight CJ.  Five new cases of primary renal carcinoid tumor: Case reports and literature reviewPathol Oncol Res. 2018 Oct 25. 

Audenet F, Isharwal S, Cha EK, Donoghue MTA, Drill E, Ostrovnaya I, Pietzak EJ, Sfakianos JP, Bagrodia A, Murugan P, Dalbagni G, Donahue TF, Rosenberg JE, Bajorin DF, Arcila ME, Hechtman JF, Berger MF, Taylor BS, Al-Ahmadie HA, Iyer G, Bochner BH, Coleman J, Solit DB. Clonal relatedness and mutational differences between upper tract and bladder urothelial carcinoma. Clin Cancer Res. 2018 Oct 23.

Upcoming events of interest or things to do

The next LMP Research Forum is scheduled for Thursday, December 13 from 5-7 in the Dale Shephard room at the Campus Club.  Kaylee Schwertfeger will present.

The Pathway to Publication workshop is scheduled for Dec. 6, 12:30 - 4pm in the McNamara Alumni Center.  All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop on how to write for peer-reviewed journals.  Here is the link to register.


The next MPG quarterly meeting is scheduled for Wednesday, December 5 from 12-1:30 in Campus Club rooms A, B, C. 

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Gold-headedCane.jpg

Publication date: 
Monday, December 3, 2018

LMP News, November 5, 2018

Koob awarded NIH funding to study tau protein in tauopathy

Michael Koob is co-PI with Dezhi Liao and lead PI Karen Ashe in a five-year $3 million NIH NIA award to study “The role of tau cleavage and phosphorylation in tauopathy."

El-Ashry receives funding to study breast cancer metastasis

Dorraya El-Ashry has been awarded a two-year $200,000 grant to "Eliminate breast cancer metastasis by targeting the tumor microenvironment."  The award is from Metavivor, a foundation funding metastatic breast cancer research.

Czyzyk awarded American Diabetes Association grant

Jan Czyzyk has been awarded a $99,343 research grant by the American Diabetes Association to study “The role of serpin immunity in human type l diabetes and beta cell proliferation.”  The grant is a re-award to the University from Czyzyk’s previous institution, the University of Rochester.

Killeen appointed MHealth Fairview Executive Medical Director for Lab/Pathology

Tony Killeen has assumed the executive medical director role for Lab/Pathology for MHealth Fairview.  This role will ensure strong academic physician leadership in a key shared clinical area and will work in dyadic partnership with laboratory and pathology administrative leaders.  

Powell receives Distinguished Pathologist Award

Debbie Powell received the Distinguished Pathologist Award for her outstanding contributions to the Twin Cities’ pathology community at the annual E.T. Bell symposium.  Debbie has spent her entire career dedicated to outstanding laboratory medicine and pathology training and medical education. 

Konety named CEO of University of Minnesota Physicians

Badrinath Konety, MD, MBA has been named the new CEO of University of Minnesota Physicians (UMP) and Vice Dean of Clinical Affairs for the Medical School.  Dr. Konety is a nationally and internationally recognized expert on prostate and bladder cancer and proven academic and clinical leader. He currently serves as the Dougherty Family Chair in Uro-Oncology, Director of the Institute for Prostate and Urologic Cancers, and the Medical School’s Associate Dean for Strategy and Innovation.  He will assume his new role December 1.   

Saenger takes on new role at HCMC

Amy Saenger, associate professor, is leaving the University this month to take a position as director of labs at Hennepin County Medical Center.  She will continue to have a faculty appointment in the department.  A search for a clinical chemist is underway. 

Celebrate our people on December 6

Once a year we gather to recognize our LMP faculty, staff and students and our UMMC laboratory staff.  The event is scheduled in The Graduate Hotel in the ballroom from 3 – 7 pm.  There will be food and just for fun teach building casino games.  Hope to see you there! 

Open Enrollment is underway

Open Enrollment began November 1 and runs through November 30.  The enrollment period is your one time during the year to review your benefit selections and make a change without a qualifying event.  The choices you make during Open Enrollment take effect on January 1, 2019.  Go to MyU/MyBenefits to make your selections. 

Medical School research and equipment grants deadline approaching

Research and equipment grants are awarded to Medical School faculty for basic and clinical research. Priority is given to startup funding for new faculty, bridge funding during lapses of an NIH R01 or similar type grants, and equipment funding.  Applications for bridge funding now have four deadlines per year including December 15.

MCC Peer Review Program offers internal peer review assistance

The Peer Review Program through the Masonic Cancer Center’s Research Development Office offers MCC members the opportunity to submit documents for internal peer review prior to external submission. This service is available for a range of documents and can be solicited at any stage throughout the grant/manuscript writing and revision process.  Find more information here.

Medical School offers P3 program to help with grant writing

Assistant professors and early-career associate professors are encouraged to apply to the AHC Proposal Preparation Program (P3) being offered this fall.  This program provides interactive, peer grant writing group support for early-career faculty to help prepare for their first K-or R-series NIH grant proposal.  Deadline is November 30.  For more information, look here

Faculty publish

Pelaez F, Manuchehrabadi N, Roy P, Natesan H, Wang Y, Racila E, Fong H, Zeng K, Silbaugh AM, Bischof JC, Azarin SM. 2018. Biomaterial scaffolds for non-invasive focal hyperthermia as a potential tool to ablate metastatic cancer cells. Biomaterials. 2018 Jun;166:27-37. doi: 10.1016/j.biomaterials.2018.02.048. Epub 2018 Feb 28.

Altawallbeh G, Smith L, Lewis SJ, et al. Pharmacokinetic study of Sudaxine in dog plasma using novel LC–MS/MS method. Drug Test Anal. 2018;1–8. https://doi.org/10.1002/dta.2507    

Upcoming events of interest or things to do

An LMP Clinical Faculty meeting is scheduled for Wednesday, November 7 at 9:00 am (right after Grand Rounds) in 450 MCRB. 

November’s LMP Research Forum scheduled for Thursday, November 8 from 5-7 in the Dale Shepard room at the Campus Club.  Nathan Pankratz will present.

Mark your calendars for the Fall Forum hosted by University of Minnesota Medical School Dean Jakub Tolar, MD, PHD, and Fairview President and CEO James Hereford to discuss the M Health Fairview clinical partnership.  The forum will take place Nov. 14, 3:30-4:30 pm. in room 2-530 Moos Tower and Nov. 15, 3:30-4:30 pm. in Wilf Auditorium on the West Bank.

The Pathway to Publication workshop is scheduled for Dec. 6, 12:30 - 4pm in the McNamara Alumni Center.  All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop on how to write for peer-reviewed journals.  Here is the link to register.


The Campus Club is offering a fall membership discount from Sept.-Dec. 2018. Receive a 60% discount off of your first year dues.  

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, November 5, 2018

LMP News, October 8, 2018

Hogquist awarded NIAID R01 grant

NIH’S National Institute of Allergy and Infectious Diseases (NIAID) has awarded Kristin Hogquist a 5-year $2.34 million R01 grant to study “The role of thymic type I interferon in tolerance.”

Tsai receives NIH-NICHD research contracts

NIH’s NICHD has awarded Mike Tsai a 2-year $1.82 million contract for “Measurement of opioids, dietary factors and genetics in the FAZST-IDEAL studies.”  NICHD also has awarded Tsai a 2-year  $315,000 contract for “Measurement of leptin in the FAZST-IDEAL studies.”

Saenger is PI of major ARDL study

Amy Saenger is laboratory PI of a $1.38 million ancillary study entitled "Changes in FGF-23 from mid- to late-life: patterns, predictors, and consequences" as part of the ARIC (Atherosclerosis Risk in Communities) cohort. This is the first high-volume study that will utilize ARDL’s mass spec instruments. ARDL will test 7,000 samples for 25-OH-vitamin D using LC-MS/MS (as well as chemistry and ELISA testing). 

New medical directors named

Congratulations are in order to the following faculty for their recent appointments as medical directors:

  • Elizabeth Courville - Medical Director of Flow Cytometry.
  • Pawel Mroz - Medical Director of Core Hematology Labs (UMMC East, West, and CSC).
  • Sarah Williams - Medical Director of Clinical Labs, MHealth, Maple Grove Clinic.

M Health Fairview definitive agreement approved

A definitive clinical partnership agreement was approved Sept. 28 by the University of Minnesota Board of Regents and the boards of University of Minnesota Physicians (UMP) and Fairview Health Services.  The agreement defines the way forward to co-create a nationally-renowned academic health system. It will combine academic and community capabilities to provide the best clinical care while supporting research and education across the shared care delivery system. “Together, we will advance our shared mission to heal, discover new treatments and cures and to educate healthcare professionals to help people lead longer, healthier lives,” according to the announcement.  Click here for more information.

Skubitz gives talk on advances in ovarian cancer detection

Amy Skubitz gave a lecture at the 12th Biennial Ovarian Cancer Research Symposium presented by the Rivkin Center for Ovarian Cancer and the American Association for Cancer Research.  The symposium was held at the University of Washington in Seattle last month.  The title of her lecture was “Development of a multi-protein classifier for ovarian cancer detection by simultaneous measurement of 92 serum proteins on Proseek Multiplex Oncology II plates.”  Skubitz also gave a talk "Ovarian cancer early detection using biomarkers" at Boston Scientific headquarters in Maple Grove as part of the company’s Ovarian Cancer Awareness Symposium in September.

Khalifa to give talk at Healthcare Information and Management Systems Society conference

Mahmoud Khalifa is an education speaker at the annual Global Conference of the Healthcare Information and Management Systems Society (HIMSS), February 11–15, 2019 at the Orange County Convention Center in Orlando, Florida.  HIMSS is the leading health information and technology conference, bringing together 45,000 professionals from more than 90 countries.  The title of Khalifa’s talk is “Postanalytic risk reduction in pathology results reporting.”  

Linden to present at CAP19

Mike Linden's peer-reviewed course, "Flow Cytometry Based on the Revised WHO Classification: Key Diagnoses That You Never Want to Miss" has been accepted for presentation at the CAP19 Annual Meeting at the Gaylord Palms in Orlando, Florida.   Linden will be presenting with Bill Karlon (Director of Flow Cytometry, UCSF) and David Dorfman (Director of Flow Cytometry, Brigham and Women's/Dana Farber).  This course will also be presented at subsequent CAP meetings in 2020 and 2021.

43rd E.T. Bell Pathology Symposium slated for Oct. 26

The 43rd E. T. Bell Pathology Symposium will be held Oct. 26 at the McNamara Alumni Center.  This year’s theme is Dermatopathology and Pathology of Superficial Soft Tissue Lesions (pdf).  The symposium is jointly sponsored bythe E. T. Bell Institute of Pathology, LMP, and Innovative Continuing Education, LLC.

Residency Video is updated

Check out our new video on the residency and fellowship programs.  The video gives a brief look at our programs, the department and the Twin Cities.  It is posted on our residency site.  Thanks to Amy Karger, Meghan Hupp, Cade Arries and Victor Santiago for helping in the video production.  https://www.pathology.umn.edu/residency-fellowships

Step up to interview residents

Resident interview season is here.  Please volunteer to spend some time interviewing candidates.  Your experience with your own training and as a faculty member in our department are important “selling” points for candidates looking at the University of Minnesota.  Upcoming interview days are scheduled for: October 29, November 2, 5, 9, 12, 19, 30 and December 3.  Please email Michelle Dolan, dolan009@umn.edu, and Maggie McGough, truax031@umn.edu, and let them know you’d be happy to interview. 

Get Your Wellbeing Points at Boynton

Participating the UPlan's Wellbeing Program is a great way to improve your health and lower the cost of your health insurance. Whether you need to earn 500 points to save $500, or 750 points to save $750, you can earn all your Wellbeing Points at Boynton!  Click this link for more information.

Faculty publish

Saenger AK, Berkwits M, Carley S, Haymond S, Ennis-O'Connor M, Sherbino J, Smith SW.  The power of social media in medicine and medical education: Opportunities, risks, and rewards. Clin Chem. 2018 Sep;64(9):1284-1290. doi: 10.1373/clinchem.2018.288225. 

Block DR, Ouverson LJ, Wittwer CA, Saenger AK, Baumann NA.  An approach to analytical validation and testing of body fluid assays for the automated clinical laboratory.  Clin Biochem. 2018 Aug;58:44-52. doi: 10.1016/j.clinbiochem.2018.05.002.

Selvin E, Warren B, He X, Sacks DB, Saenger AKEstablishment of community-based reference intervals for fructosamine, glycated albumin, and 1,5-anhydroglucitol.  Clin Chem. 2018 May;64(5):843-850. doi: 10.1373/clinchem.2017.285742.

Danni Li, Fangying Huang, Yingchun Zhao, Peter W. Villata, Timothy J. Griffin, Lin Zhang, Ling Li and Fang Yu.  Plasma lipoproteome in Alzheimer’s disease: a proof-of-concept study.  Clinical Proteomics2018; 15:31  https://doi.org/10.1186/s12014-018-9207-z

Upcoming events of interest or things to do

The annual MPG Symposium will be held October 11 at Coffman Memorial Union with keynote speaker Muneesh Tewari from the University of Michigan.  His keynote talk is at 2 pm.  Tewari will discuss the integration of cell free DNA with wearable sensors for early cancer diagnosis. 

The 8th Great Lakes Nuclear Receptors Conference will be held Oct. 18-19 in the Cancer and Cardiovascular Research Building (CCRB).  The regional meeting brings together senior investigators and their trainees whose research is focused on nuclear receptor biology.

Grand Rounds are back on Wednesday’s at 8:00 am in 450 MCRB (Masonic Cancer Research Building)

LMP’s Research Forum resumes Thursday, Oct 18, 5 pm. in the Dale Shephard Room of the Campus Club in Coffman Union.

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, October 8, 2018

LMP News, September 24, 2018

Tsai receives NIH-NICHD research contracts

NIH’s NICHD has awarded Mike Tsai a 2-year $2.45 million contract for “Measurement of biospecimens in the FAZST-IDEAL Studies,” which are designed to determine if an intervention comprising folic acid and zinc dietary supplementation improves semen quality and fertility outcomes among couples seeking assisted reproduction.  NICHD also has awarded Tsai a $434,000 contract for the pregnancy eating attributes study (PEAS) for microbiome studies and analysis of serum biomarkers to explore the differences in lipid and glucose homeostasis and lipid/fat metabolism.

Schwertfeger awarded NIH funding to study macrophages in mammary gland development

NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has awarded Kaylee Schwertfeger a 5-year $1.92 million R01 grant to study “Regulation of tissue resident macrophages during mammary gland development.”

Leadership change in Molecular Diagnostics Laboratory

Sophia Yohe has been named the Medical Director of the Molecular Diagnostics laboratory.  In this role, Yohe will provide oversight for the clinical operations of the lab.  Thank you to our previous medical director, Bharat Thyagarajan, for his years of outstanding leadership. 

Murugan is guest lecturer

Paari Murugan presented a guest lecture and slide seminar on "Approach to diagnosis of soft tissue tumors" to pathology residents at McGill University, Montreal, August 13

LMP adds facilities and research support

Caroline Hallstrom starts today as a research professional in LMP.  In her role, Caroline will take over responsibilities for LMP facilities.  She will keep our space inventory up to date, help with space requests and new laboratory set ups.  Additionally, she will provide as needed research lab support.  Caroline has several years of experience working in laboratories at the University, joining us from Martin Felice’s lab in the Cancer Center.  Caroline is located in 760 Mayo and her phone number is 612-625-0441.  Hallstrom will report to Nicole Hilmoe.  

43rd E. T. Bell Pathology Symposium slated for Oct. 26

The 43rd E. T. Bell Pathology Symposium will be held Oct. 26 at the McNamara Alumni Center.  This year’s theme is Dermatopathology and Pathology of Superficial Soft Tissue Lesions (pdf).  The symposium is jointly sponsored bythe E. T. Bell Institute of Pathology, LMP, and Innovative Continuing Education, LLC.

ALRT asks for early notice of grant applications

If you’re planning to submit a grant proposal, please let Carol El-Ghandour know well in advance whenever possible (for example, 2 months ahead of the deadline for a federal grant).  This will ensure a great spot in the grant queue.  Carol can be contacted at elgha001@umn.edu or 612-625-8468. 

Pankratz moves to Mayo Building

Nathan Pankratz and his team recently moved their offices from the first floor of Moos Tower to the seventh floor of Mayo where they actually have windows.  The remodeled space includes a conference room and room to expand the department’s evolving division of computational pathology. 

Kurata hits employment milestone

Jean Kurata has hit the 45-year milestone as a University employee.  After earning a B.S. degree from the University in elementary education and working at the Hormel Institute, in 1973 she took a job in the College of Education’s Student Affairs Office, providing staff support.  Then she was an assistant in the College’s Office of the Dean for nine years.  She joined LMP in 1993 as assistant to LMP head Leo Furcht.  Congratulations Jean!

Hoffman joins GWG public relations committee

Bill Hoffman has joined a newly formed public relations committee of the Genome Writers Guild (GWG).  GWG is devoted to advancing the new field of genome editing throughout the life sciences. Bill previously served on the public education committee of the International Society for Stem Cell Research (ISSCR).

Faculty publish

Amin K, El-Rayess D, Snover D, Mettler T, Vogel RI, Khalifa MAPatterns of Immunohistochemistry Utilization in Metastases to the Liver. Appl Immunohistochem Mol Morphol. 2018 Sep 5. [Epub ahead of print].  

Alanee, S, Alvarado-Cabrero, I, Murugan, P, Kumar, R, Nepple, KG, Paner, GP, Patel, MI, Raspollini, MR, Lopez-Beltran, A & Konety,  Update of the International Consultation on Urological Diseases on bladder cancer 2018: Non-urothelial cancers of the urinary bladder. World Journal of Urology. 2018 Aug 1. DOI: 10.1007/s00345-018-2421-5 

Glumac PM, Forster CL, Zhou H, Murugan P, Gupta S, LeBeau AM. The Identification of a Novel Antibody for CD133 Using Human Antibody Phage Display. Prostate. 2018 Sep;78(13):981-991.

Ganaie A, Beigh FH, Astone M, Ferrari MG, Maqbool R, Umbreen S, Parray AS, Siddique HR, Hussain T, Murugan P, Morrissey C, Koochekpour S, Deng Y, Konety BR , Hoeppner LH, Saleem MB. BMI1 drives metastasis of prostate cancer in Caucasian and African-American men and is a potential therapeutic target: hypothesis tested in race-specific models. Clin Cancer Res. 2018 Aug 7.  DOI: 10.1158/1078-0432.CCR-18-1394

Bellamri M, Weight CJ, Murugan P, Turesky RJ. Metabolic activation of the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in human prostate.  Toxicol Sci. 2018 Jun 1;163(2):543-556.

Upcoming events of interest or things to do

The annual MPG Symposium will be held October 11 at Coffman Memorial Union with keynote speaker Muneesh Tewari from the University of Michigan.  Tewari will discuss the integration of cell free DNA with wearable sensors for early cancer diagnosis.  Faculty should encourage research laboratory staff to attend the symposium and participate in the career networking session from 1-2 pm. 

NCI SBIR Program Director Ashim Subedee will be presenting funding opportunities and other commercialization resources to take your technology from lab to market, Oct 1,  9 – 10:30 am, in 450 MCRB. Register here.

The 8th Great Lakes Nuclear Receptors Conference will be held Oct. 18-19 in the Cancer and Cardiovascular Research Building (CCRB).  The regional meeting brings together senior investigators and their trainees whose research is focused on nuclear receptor biology. 

Grand Rounds are back on Wednesday’s at 8:00 am in 450 MCRB (Masonic Cancer Research Building)

LMP’s Research Forum resumes Thursday, Oct 18, 5 pm. in the Dale Shephard Room of the Campus Club in Coffman Union.

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, September 24, 2018

LMP News, September 10, 2018

Hogquist named LMP Vice Chair for Research

Congratulations are in order for Kris Hogquist who has been named LMP’s Vice Chair for Research.  In this new role, Kris will serve as chair of the department’s Research Advisory Committee (RAC), identify strategic initiatives to expand on the department’s existing research accomplishments and help support the chair’s research vision for the department. 

Koob awarded NIH funding to study key tau tangles protein

NIH’s aging research program awarded Michael Koob a two-year grant totaling $423,500 to study “Molecular endophenotypes of H1 and H2 MAPT haplotypes.”  MAPT (micro-tubule associated protein) encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer’s disease.

American Association of Immunologists funds Hamilton Hart study

The American Association of Immunologists awarded Sara Hamilton Hart $48,432 to study “Bystander activation through natural pathogen exposure shapes the memory CD8 T cell pool.”

LMP residents nominated to participate in U of M Resident Leadership Academy

Second-year residents Cade Arries and Aimi Toyama have been nominated to participate in the fifth cohort of the U of M Resident Leadership Academy, a one-year program for residents selected for their current leadership skills and future potential to transform healthcare.

Biostatistics support now available

LMP has engaged the Biostatistical Design and Analysis Center (BDAC) to provide biostatistics support for research.  Visit the LMP faculty Google site to review the request process for requests.    

National Postdoc Appreciation Week is coming soon

National Postdoc Appreciation Week is Sept. 17-21.  Click this link for U of M activities.

Dockter takes on new role in Medical School

Kathleen Dockter, ALRT Center Director, has been appointed Senior Director of Operational Alignment.  Kathleen will serve as project manager for the operational alignment work across the Medical School and UMPhysicians as the organization moves forward with the joint clinical enterprise with Fairview. 

NCI’s SBIR program director to visit Masonic Cancer Center

NCI SBIR Program Director Ashim Subedee will be presenting funding opportunities and other commercialization resources to take your technology from lab to market, Oct 1,  9 – 10:30 am, in 450 MCRB. Register here.

New center aims to streamline clinical research support

The newly established Clinical Research Support Center (CRSC), located on the third floor of Diehl Hall, opened Sept. 4. The CRSC will give U of M investigators and study teams an easier way to navigate the complex clinical research environment and advance research projects through the process more quickly. The CRSC is a partnership between the Office of the Vice President for Research, the Clinical and Translational Science Institute, Fairview Health Services, and University of Minnesota Physicians.

Medical School launches Research Connect initiative

Dean Tolar announced that the Medical School has launched a new initiative, Research Connect, a resource to communicate medical student/resident research opportunities. “This is a great way for our clinical learners to connect with science and scientists,” Tolar said.

Clarification

Danni Li’s four-year NIH R01 grant to study “Blood Biomarkers as Surrogate Endpoints of Treatment Responses to Aerobic Exercise and/or Cognitive Training in Amnestic Mild Cognitive Impairment” is for $1.95 million.  $491,000 is allotted for the first year.

Correction

Ameeta Kelekar will introduce the keynote speaker at the Center for Women in Medicine and Science’s first annual retreat Sept. 27 in theCancer and Cardiovascular Research Building, not the Center for Women and Science. 

Faculty publish

Yuan JM, Carmella SG, Wang R, Tan YT, Adams-Haduch J, Gao YT, Hecht SSRelationship of the oxidative damage biomarker 8-epi-prostaglandin F2α to risk of lung cancer development in the Shanghai Cohort Study.  Carcinogenesis. 2018 Jul 3;39(7):948-954. doi: 10.1093/carcin/bgy060.

Owen DL, Mahmud SA, Vang KB, Kelly RM, Blazar BR, Smith KA, Farrar MA.  Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis.  J Immunol. 2018 Jun 15;200(12):3926-3933. doi: 10.4049/jimmunol.1800097. Epub 2018 May 4.

Nelson AC, Machado HL, Schwertfeger KLBreaking through to the other side: Microenvironment contributions to DCIS initiation and progression. J Mammary Gland Biol Neoplasia. 2018 Aug 31. doi: 10.1007/s10911-018-9409-z. [Epub ahead of print] Review.

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

Upcoming events of interest or things to do

The annual MPG Symposium will be held October 11 at Coffman Memorial Union with keynote speaker Muneesh Tewari from the University of Michigan.  Tewari will discuss the integration of cell free DNA with wearable sensors for early cancer diagnosis.  

The 8th Great Lakes Nuclear Receptors Conference will be held Oct. 18-19 in the Cancer and Cardiovascular Research Building (CCRB).  The regional meeting brings together senior investigators and their trainees whose research is focused on nuclear receptor biology. 

Grand Rounds are back on Wednesday’s at 8:00 am in 450 MCRB (Masonic Cancer Research Building)

A reminder that LMP’s Research Forum resumes Thursday, Oct 11, 5 pm. in the Dale Shephard Room of the Campus Club in Coffman Union.

  

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, September 10, 2018

LMP News, August 20, 2018

Li awarded NIH grant to investigate biomarkers associated with mild cognitive impairment

NIH’s National Institute on Aging has awarded Danni Li a four-year R01 grant in the amount of $491,000 to study “Blood Biomarkers as Surrogate Endpoints of Treatment Responses to Aerobic Exercise and/or Cognitive Training in Amnestic Mild Cognitive Impairment.” 

Linden joins Steering Committee for MDS-AML education program

MikeLinden recently joined the Steering Committee for MDS+AML MATTER, a free education program focused on myelodysplastic syndrome and acute myeloid leukemia that offers continuing education credit. It is hosted in partnership by the American Society of Hematology, American Society for Clinical Pathology, National Marrow Donor Program, Oncology Nursing Society, and The France Foundation.  Mike will design course curricula and will be presenting at four meetings this fall.

MPG Symposium slated for October 11

The annual MPG Symposium will be held October 11 at Coffman Memorial Union with keynote speaker Muneesh Tewari from the University of Michigan.   Tewari is Ray and Ruth Anderson-Laurence Sprague Memorial Research Professor, Professor of Internal Medicine, and Professor of Biomedical Engineering.  He is also affiliated with the Department of Computational Medicine and Bioinformatics.

Tewari will discuss the integration of cell free DNA with wearable sensors for early cancer diagnosis.  

Kelekar to introduce keynote speaker at Center for Women and Science retreat

Ameeta Kelekar will introduce keynote speaker Deborah Streeter, theBruce F. Failing Sr. Professor of Personal Enterprise and Small Business Managementat Cornell University, at theCenter for Women and Science’s first annual retreat Sept. 27 in theCancer and Cardiovascular Research Building.

MCC pre-R01 pilot grant proposal deadline approaching

The deadline to apply for the Masonic Cancer Center’s pre-R01 pilot grants program is Sept. 17. The grants will be awarded through a competitive peer review process. It is anticipated that 1-2 projects will be funded for up to $100,000 each in the current cycle. These grants are intended to support new research ideas that address the MCC Scientific Priorities for Growth.

Medical School research and equipment grants available

Research and equipment grants are awarded to Medical School faculty for basic and clinical research. Priority is given to startup funding for new faculty, bridge funding during lapse of an NIH R01 or similar type grant, and equipment funding.  Assistant Professor Startup Funding and Equipment Funding grant applications are received two times per year including September 15. Applications for bridge funding now have four deadlines per year including September 15

U of M Grant-in-Aid funding available

The Grant-in-Aid of Research, Artistry, and Scholarship program (GIA) promotes the research, scholarly, and artistic activities of faculty and supports academic excellence throughout the University.  Grant-in-Aid funds act as seed money for developing projects to the point of attracting more complete, external funding.  In fiscal year 2017, 84 grants were awarded with an average award of $33,000.  GIA application deadline is Sept. 17

Applications for the Health Equity Leadership & Mentoring Fellowships now being accepted

The Health Equity Leadership & Mentoring Program (HELM) is designed to enhance the academic excellence and leadership capacity of diverse faculty and health disparities researchers at the University of Minnesota and ultimately reduce health inequities. HELM addresses some of the challenges that faculty and postdoctoral fellows/trainees from minority and underserved communities and other faculty whose research focuses on health equity may face in the academic setting. Applications will be accepted through Sept. 10 or until the 10 slots available are filled.

Chainbreaker bicyclists hit the road

The second annual Chainbreaker bike ride (25 – 180 miles) took place August 10- 12 under sunny skies and very warm temperatures.  Last year more than a thousand riders helped to raise nearly $1.4 million for the Masonic Cancer Center.  Donations are accepted through Oct. 12.  Go to https://chainbreakerride.org/ to donate.

Residents, fellows and pathologist assistants gather for group photo

See the photo at the bottom of the newsletter.

Faculty publish

Hogquist KA and Hamilton SEFor T cells, the child Is father of the man [Commentary].  Cell. 2018; 174(1): 16-18. https://doi.org/10.1016/j.cell.2018.06.015

Flanagan ME, Keene CD, Louis DN and Gordana J-S.  Localized crystal-storing histiocytosis of the posterior fossaNeuropathology. 2018 Jul 31. doi: 10.1111/neup.12486. [Epub ahead of print] 

Martin AM, Nirschl CJ, Polanczyk MJ, Bell WR, Nirschl TR, Harris-Bookman S, Phallen J, Hicks J, Martinez D, Ogurtsova A, Xu H, Sullivan LM, Meeker AK, Raabe EH, Cohen KJ, Eberhart CG, Burger PC, Santi M, Taube JM, Pardoll DM, Drake CG, Lim M.  PD-L1 expression in medulloblastoma: an evaluation by subgroup.  Oncotarget. 2018 Apr 10;9(27):19177-19191. doi: 10.18632/oncotarget.24951

Bell WR, Meeker AK, Rizzo A, Rajpara S, Rosenthal IM, Flores Bellver M, Aparicio Domingo S, Zhong X, Barber JR, Joshu CE, Canto-Soler MV, Eberhart CG, Heaphy CM.  A unique telomere DNA expansion phenotype in human retinal rod photoreceptors associated with aging and disease.  Brain Pathol. 2018 Apr 18. doi: 10.1111/bpa.12618. [Epub ahead of print] 

Kline SE, Neaton JD, Lynfield R, Ferrieri P, Kulasingam S, Dittes K, Glennen A, Jawahir S, Kaizer A, Menk J, Johnson JR.  Randomized controlled trial of a self-administered five-day antiseptic bundle versus usual disinfectant soap showers for preoperative eradication of Staphylococcus aureus colonization.  Infect Control Hosp Epidemiol. 2018 Jul 24:1-9. doi: 10.1017/ice.2018.151. [Epub ahead of print]

Arbefeville S, Nelson K, Thonen-Kerr E, Ferrieri PProspective postimplementation study of Solana Group A streptococcal nucleic acid amplification test vs conventional throat culture. Am J Clin Pathol. 2018 Jul 5. doi: 10.1093/ajcp/aqy051. [Epub ahead of print]

Gilles SR, Arbefeville SSFerrieri P, Courville ELLymph node with extensive involvement by Cryptococcus shortly following liver transplantation.  Lab Med. 2018 Jul 5;49(3):e78-e81. doi: 10.1093/labmed/lmy021.

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

Upcoming events of interest or things to do 

The U of M Farmers Market takes place Wednesdays, 11 a.m.-2 p.m., Gateway Plaza outside McNamara Alumni Center through Sept. 26. Local farmers are looking forward to bringing you the freshest vegetables, berries, flowers, and more. Once again there will be plenty of dining options including the UDS dining tent and several food trucks. Representatives from the U of M's Wellbeing Program will be handing out t-shirts.

There's still time to earn wellbeing points to save money on UPlan premiums. Points must be earned by August 31https://humanresources.umn.edu/wellbeingprogram

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

LMP residents group photo

Publication date: 
Monday, August 20, 2018

LMP News, July 30, 2018

Pediatrics to honor Ferrieri

Pat Ferrieri was named as the Gold-Headed Cane Awardee by the U of M Department of Pediatrics for 2018. This award honors life-long service to children.  Ferrieri will be awarded the cane at Peds Grand Rounds, 7:30 am on Oct. 31 in the Wilf Auditorium.

Killeen awarded NIH funding for myocardial fibrosis research

Tony Killeen was awarded a $105,700 NIH research grant to study “Myocardial fibrosis in hypertensive adults with and without CKD.”  The award is a subcontract from Case Western Reserve University.

Karger receives Siemens contract

Amy Karger received a $22,000 contract from Siemens Medical Solutions USA, Inc. for laboratory specimen collection services.

LMP faculty attend CAP meeting

Tony Killeen, Mike Linden and Sophia Yohe attended CAP’s Council on Scientific Affairs meeting in Vail, Colorado July 14.  See photo below.

Salary Savings awarded

This is the third year that LMP has awarded salary savings funds to faculty who have covered more than 50% of their University compensation through grants.  Four faculty will receive discretionary funds.  Awards range from $10,000 to $20,000 and are made annually based on July 1 funded effort. Faculty who hold chairs or professorships are not eligible for the program.

ALRT gets new HR Manager

Troy Stevermer will be joining the University of Minnesota Medical School as Human Resources Manager for the ALRT Administrative Center.  Troy's first day will be Tuesday, July 31.  Troy comes to the U from Healthpartners in the role of Director of Human Resources for Capitol View Transitional Care Center.  Prior to that, Troy held human resources positions in Northwest Airlines, Federal Express and Mayo Foundation.  Troy has a Master of Science in Industrial Relations degree and a Bachelor or Science in Psychology degree, both from Iowa State University.  Troy's office will be located on 7th Floor Mayo in the Laboratory Medicine & Pathology / ALRT Center Office suite.  His email is steve771@umn.edu and phone number is 612-625-3682.  

McGough welcomes baby girl

A new addition to the McGough family arrived July 17; Maggie and her husband welcomed a daughter, Zoey Anne.  See photo attached at the end of this newsletter. Everyone is happy and doing well.

Faculty publish

Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KAJameson SCThe purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.  Nature. 2018 Jul;559(7713):264-268. doi: 10.1038/s41586-018-0282-0. Epub 2018 Jul 4.

Afiuni-Zadeh, S., Boylan, K.L.M., Jagtap, P.D., Griffin, T.J., Rudney, J.D., Peterson, M.L., and Skubitz, A.P.N.  Evaluating the potential of residual Pap test fluid as a resource for the metaproteomic analysis of the cervical-vaginal microbiome.  Scientific Reports. 2018; 8:10868. doi:10.1038/s41598-018-29092-4.

Kurant DE, Baron JM, Strazimiri G, Lewandrowski KB, Rudolf JW, Dighe AS. Creation and use of an electronic health record reporting database to improve a laboratory test utilization program. Appl Clin Inform. 2018;09(03):519-527.

Rashidi A, Ebadi M, Shields-Cutler RR, DeFor TE, Al-Ghalith GA, Ferrieri P, Young JH, Dunny GM, Knights D, Weisdorf DJ.  Pretransplant gut colonization with intrinsically vancomycin-resistant enterococci (E. gallinarum and E. casseliflavus) and outcomes of allogeneic hematopoietic cell transplantation.  Biol Blood Marrow Transplant. 2018 Jun;24(6):1260-1263. doi: 10.1016/j.bbmt.2018.01.025. Epub 2018 Jan 31.

Vahidi S, Beckman A, Albrecht K, Arbefeville SFerrieri P, Amin KUrinary tract blastomycosis diagnosed by urine cytology.  Diagn Cytopathol. 2018 Mar 23. doi: 10.1002/dc.23929. [Epub ahead of print]

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

Upcoming events of interest or things to do

The U of M Farmers Market takes place Wednesdays, 11 a.m.-2 p.m., Gateway Plaza outside McNamara Alumni Center through Sept. 26. Local farmers are looking forward to bringing you the freshest vegetables, berries, flowers, and more. Once again there will be plenty of dining options including the UDS dining tent and several food trucks. Representatives from the U of M's Wellbeing Program will be handing out t-shirts.

Northrop's Music on the Plaza series continues on Wednesdays, noon-1 p.m., through Aug. 1. The program has been a campus tradition since the 1950s and features bands of all genres. Bring a lunch, find a seat, and dance along to the sounds of local musicians.

There's still time to earn wellbeing points to save money on UPlan premiums. Points must be earned by August 31.  https://humanresources.umn.edu/wellbeingprogram

Chainbreaker rider signup is still available!  Visit https://chainbreakerride.org/ to register or get more information.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

CAP

Zoey

 

 

Publication date: 
Monday, July 30, 2018

LMP News, July 16, 2018

Li awarded NIH grant to investigate neurodegeneration biomarkers

NIH’s National Institute on Aging has awarded Danni Li $253,000 for “Identification of plasma hydroxysphingolipids as biomarkers of demyelination and neurodegeneration underlying physical function decline in older adults.”

Farrar receives Cancer Center funds

Mike Farrar and David Potter, Department of Medicine, recently received Masonic Cancer Center funds ($50,000) to investigate the “Potentiation of Immune Checkpoint Blockade by Inhibition of Epoxyeicosatrienoic Acid Driven Tumor Respiration.”

Balfour receives foundation award for EBV vaccine research

The Matt Cwiertny Memorial Foundation has awarded Hank Balfour $10,000 for his team’s research on EBV vaccine.  Matt Cwiertny died at the age of 23 from complications of EBV-induced autoimmune disease and cancer.

Yohe promoted July 1

Congratulations are in order for Sophia Yohe who made it through the promotion process to associate professor this year.  Congratulations Sophia!

Borges da Silva awarded postdoc fellowship

The Cancer Research Institute recently awarded Henrique Borges da Silva a three-year postdoctoral fellowship for his work on “Harnessing CD8+ T cell antitumor responses by manipulating extracellular ATP signaling”.  Borges da Silva works in Steve Jameson’s laboratory.

Innovation Initiative Phase IV Awards announced

The department’s Innovation Initiative Awards for 2018 go to:

  • Joe Rudolf and Tony Killeen for “Early detection of sepsis using data from routine clinical laboratory tests”
  • Pawel Mroz and Bharat Thyagarajan for “Detection and quantification of BCR-ABL1 fusion transcripts in samples from patients with acute lymphoblastic leukemia by droplet digital PCR”
  • Elizabeth Courville and Nathan Pankratz for “Use of automated gating and machine learning to streamline and improve the accuracy and sensitivity of clinical flow cytometry workflows”

Killeen recognized as “Top Doctor”

Tony Killeen was recognized as one of Mpls.St.Paul magazine’s “Top Doctors” for 2018.  He joined 151 MHealth physicians so honored.

Blood Bank Guy to interview Cohn

Claudia Cohn will be interviewed by Joe Chaffin, the Blood Bank Guy, this month.  The interview will focus on “Critical Developments of 2017,” a review of transfusion medicine on which she was senior editor.

Regents approve GI Pathology Fellowship program

The Board of Regents recently approved the Medical School's application for a new GI Pathology Fellowship programOne fellow will be accepted per year and will rotate in the East and West Bank laboratories.  Trainees who have finished their AP or AP/CP training are invited to apply.

UMPhysicians transitioning to Empower Retirement

UMPhysicians will transition from its current 401(k) plan administrator, Bank of America Merrill Lynch (BOAML), to Empower Retirement August 1. UMPhysicians also will be introducing a 457(b) Deferred Compensation Plan for physicians. Both the UMPhysicians Retirement and 401(k) Savings Plan and the new 457(b) Deferred Compensation Plan will be administered by Empower.  Representatives from Empower will be hosting information sessions throughout July to provide more information.  To ensure you have the best experience, register here to come for the group session or 1-on-1 appointment which works best for you.  

NIH P3 program deadline approaching

The NIH Proposal Preparation Program (P3) is designed for early-career, assistant professor faculty members in the Medical School preparing their first K- or R-series NIH grant proposal. Applications for the Fall 2018 P3 Cycle are due July 30.

Desktop support changes

AHC-IS desktop support charges have changed from a per device charge to a departmental cost pool charge.  This change has been implemented to reduce institutional risk for individuals working in the health care component schools and centers, or working with ePHI, but not formally supporting their devices due to the cost.  All computers must be purchased thru and supported by AHC-IS.  Information on the services provided by AHC-IS can be found here:  https://hub.ahc.umn.edu/technology-information-systems/request-ahc-services.

Hoffman to give talk to the Minnesota Neuropathy Association

Bill Hoffman will give a talk titled “Stem Cells and Regenerative Medicine:  A Revolution Picks Up the Pace” to the Minnesota Neuropathy Association, 10 am. Aug. 4, at St. Michael’s Church in Bloomington, 9201 Normandale Blvd.

Faculty publish

Brett, M. E., H. E. Bomberger, G. R. Doak, M. A. Price, J. B. McCarthy and D. K. Wood. "In vitro elucidation of the role of pericellular matrix in metastatic extravasation and invasion of breast carcinoma cells." Integr Biol (Camb) 2018; 10(4): 242-252.

McCarthy, J. B., D. El-Ashry and E. A. Turley. "Hyaluronan, cancer-associated fibroblasts and the tumor microenvironment in malignant progression." Front Cell Dev Biol. 2018; 6: 48.

Domingo-Musibay E, Murugan PGiubellino A, Sharma S, Steinberger D, Yuan J, Hunt MA, Lou E, Miller JS.  “Near complete response to Pembrolizumab in microsatellite-stable metastatic sebaceous carcinoma.  J Immunother Cancer. 2018 Jun 19;6(1):58. doi: 10.1186/s40425-018-0357-3.

Cederberg LM, Rabinovitch MD, Grimm-Geris JM, Schmeling DO, Filtz EA, Condon LM, Balfour HH Jr. Epstein-Barr virus DNA in parental oral secretions: a potential source of infection for their young children. Clin Infect Dis 2018; DOI: 10.1093/cid/ciy464

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

Upcoming events of interest or things to do

The U of M Farmers Market takes place Wednesdays, 11 a.m.-2 p.m., Gateway Plaza outside McNamara Alumni Center through Sept. 26. Local farmers are looking forward to bringing you the freshest vegetables, berries, flowers, and more. Once again there will be plenty of dining options including the UDS dining tent and several food trucks. Representatives from the U of M's Wellbeing Program will be handing out t-shirts.

There's still time to earn wellbeing points to save money on UPlan premiums. Points must be earned by August 31https://humanresources.umn.edu/wellbeingprogram

Chainbreaker rider signup is still available!  Visit https://chainbreakerride.org/ to register or get more information.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, July 16, 2018

LMP News, June 25, 2018

Tsai to be honored with LVDD Cooper Award

Mike Tsai has been awarded the AACC Lipoproteins and Vascular Diseases Division LVDD Cooper Award, a lifetime achievement award that recognizes individuals for outstanding service contributions in the area of lipoproteins and vascular diseases.  He will receive the award at the AACC meeting in Chicago July 30. Tsai won the LVDD Zak award in 2007 for outstanding research contributions.

McIntyre joins LMP faculty

Kelsey McIntyre, PhD, DABMMG joins the LMP faculty as an assistant professor July 31.  She comes to the University from Harvard Medical School where she was a Clinical Cytogenetics Fellow (2017) and a Clinical Molecular Genetics Fellow (2018). McIntyre will be a welcome addition to the department’s initiatives in cytogenetics and molecular diagnostics. 

Regents approve Laboratory Genetics and Genomics Fellowship program

At its May meeting, the University Board of Regents approved the Medical School's application for a new Laboratory Genetics and Genomics Fellowship program in the Department of Laboratory Medicine and Pathology. The program merges two previously existing programs,  Clinical Molecular Genetics and Cytogenetics, combining key educational objectives and eliminating overlap.   Students currently enrolled in the existing programs will be supported as they complete their training. 

Russell joins Anatomic Pathology

Welcome to Nancy Russell who starts today in our anatomic pathology division office as an administrative assistant in support of the AP faculty.  Nancy comes to us from the Department of Medicine and before that the School of Public Health, where she worked for 10 years. 

Stanley retires

LMP adjunct professor Mike Stanley has retired.  Stanley was affiliated with Abbott-Northwestern Hospital and Hospital Pathology Associates, PA.

Hoffman to give talk at Genome Engineering 2018

Bill Hoffman will give a talk “Stem Cells in 3D:  How organoids illuminate development, disease, and design” at The Next Revolution: Genome Engineering 2018, July 19, 2 pm. at the McNamara Alumni Center.  His talk is part of the cell and gene therapies program.

Regents approve compensation increase 2018-19

Faculty, professional and academic salary and civil service employees are eligible for an average 2% increase for fiscal year 2018-19.  Our pay plans have been approved and increases are expected to show up on paychecks July 3.

Working to strengthen M Health

The University of Minnesota, University of Minnesota Physicians, and Fairview Health Services have announced a nonbinding letter of intent to create a nationally-renowned health system that combines academic and community resources to provide the best clinical care to patients and communities, while supporting research and education.

Funding opportunity deadline approaching

The deadline for a Letter of Intent (competitive) to apply for the Minnesota Partnership for Biotechnology and Medical Genomics is July 13.

Faculty publish

Yang R, Van Etten JL, Dehm SMIndel detection from DNA and RNA sequencing data with transIndel. BMC Genomics. 2018 Apr 19;19(1):270. doi: 10.1186/s12864-018-4671-4.

Pérez Ortiz JM, Orr HT. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies. Adv Exp Med Biol. 2018;1049:135-145. doi: 10.1007/978-3-319-71779-1_6.

Sackett K, Cohn CS, Fahey-Ahrndt K, Smith AR, Johnson AD. Successful treatment of pure red cell aplasia because of ABO major mismatched stem cell transplant. J Clin Apher. 2018 Feb;33(1):108-112. doi: 10.1002/jca.21553. Epub 2017 May 24.

Williams SM, Sumstad D, Kadidlo D, Curtsinger J, Luo X, Miller JS, McKenna DH Jr.  Clinical-scale production of cGMP compliant CD3/CD19 cell-depleted NK cells in the evolution of NK cell immunotherapy at a single institution. Transfusion. 2018 Mar 12. doi: 10.1111/trf.14564.

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

Upcoming events of interest or things to do

There's still time to earn wellbeing points to save money on UPlan premiums. Points must be earned by August 31https://humanresources.umn.edu/wellbeingprogram

Chainbreaker rider signup is now open at https://chainbreakerride.org/ to register or get more information.

Everyone needs to complete the University’s mandatory Sexual Misconduct training by June 30

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, June 25, 2018

LMP News, June 11, 2018

Pennell study achieves milestone

Chris Pennell is lead author of “Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice” published in Molecular Therapy.  Pennell, Bruce Blazar and fellow investigators from the immunotherapy group at the Masonic Cancer Center developed a mouse model that can predict potentially life-threatening complications from CAR T immunotherapy.  In a commentary accompanying the article, CAR T therapy pioneer Carl June and colleague Marco Ruella called the report “a milestone in the development of preclinical models able to predict human CAR T toxicity and efficacy.”

Pankratz and Hirsch investigate myelodysplastic syndrome in Minnesota

Nathan Pankratz and Betsy Hirsch are co-investigators of a five-year NCI R01 grant “Predictors of myelodysplastic syndrome in Minnesota.” Pankratz, Hirsch and fellow investigators will receive $600,000 for the first year of the grant period.

Hamilton Hart awarded careers in immunology fellowship

Sara Hamilton Hart has been awarded a American Association of Immunologists 2018 Careers in Immunology Fellowship. The fellowship supports the career development of young scientists by providing eligible PIs with one year of salary support for a trainee in their labs.  Postdoctoral trainee Mathew Huggins will receive salary support for his work in Hamilton Hart’s laboratory. 

Tsai receives NIH contract

Mike Tsai was awarded a one-year NIH contract in the amount of $465,000 to analyze neonatal dried blood spot DNA methylation and conception by infertility treatment for the Upstate KIDS study led by the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The project is in collaboration with the New York State Department of Health and the University at Albany. 

Pathologist’s assistant joins staff in Anatomic Pathology

​Robert Gounaris will start his new position as a pathologist’s assistant June 18.  Gounaris is a graduate of Loyola University and received his M.S. Pathologist’s Assistant degree from the Rosalind Franklin University of Medicine and Science.   He worked as a grossing technician at Loyola University Medical Center from 2013 to 2016. Welcome Robert.

Nuclear receptors conference will be held on campus

The 8th Great Lakes Nuclear Receptors Conference will be held Oct. 18-19 in the Cancer and Cardiovascular Research Building (CCRB).  The regional meeting brings together senior investigators and their trainees whose research is focused on nuclear receptor biology.  Scott Dehm is one of the organizers of this year’s conference, which is being held in Minnesota for the first time.

Khalifa to give talk in Scotland

Mahmoud Khalifa will address common diagnostic challenges in gynecologic pathology at the 17th International Conference on Pathology and Cancer Epidemiology, Edinburgh, Scotland, October 8-9.

LMP faculty meeting

Slides from the May 30 LMP faculty meeting are available on the LMP Google site:  https://sites.google.com/a/umn.edu/lmp/faculty-meetings

Faculty publish

Christine Henzler, Matthew Schomaker, Rendong Yang, Aaron P. Lambert, Rebecca LaRue, Robyn Kincaid, Kenneth Beckman, Teresa Kemmer, Jon Wilson, Sophia YoheBharat ThyagarajanAndrew C. Nelson.  Optimization of a microfluidics-based next generation sequencing assay for clinical oncology diagnostics.  Annals of Translational Medicine, 2018; 6 (9).  http://dx.doi.org/10.21037/atm.2018.05.07

Kenny honored

LMP Sr. administrative director Linda Kenny was honored at a retirement reception May 23 at the Campus Club.  See photo below of Linda with LMP head Leo Furcht.   Linda joined LMP in 1982 as an education program coordinator.  After many years of dedicated service her last day was June 8.  Linda is succeeded by Nicole Hilmoe.  Feel free to contact Nicole at 612-626-4834, email: artne001@umn.edu 

Send news to Bill

Please send publications, achievement and event information and announcements you think appropriate for the LMP Newsletter to Bill Hoffman at hoffm003@umn.edu.  Also, Bill has an ongoing interest in photographs, images, and story ideas you may have for the LMP website.

Upcoming events of interest or things to do

The 4th Annual John H. Kersey Memorial Lecture is Thursday, June 21. The lecture will feature Matthew Meyerson, MD, PhD, of the Dana-Farber Cancer Institute and Harvard Medical School.  Kersey was LMP professor from 1977-2013, director of the Bone Marrow Transplant Program from 1974-1995, and a founding director of the Masonic Cancer Center.

Chainbreaker rider signup is now open at https://chainbreakerride.org/ to register or get more information. A Chainbreaker Rally for TeamU will be held June 13, 11-30-1:30 on Diehl Hall Plaza. 

Everyone needs to complete the University’s mandatory Sexual Misconduct training by June 30.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Leo&Linda

Publication date: 
Monday, June 11, 2018

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