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LMP News, August 14, 2017

CONGRATULATIONS TO OUR LMP CHAINBREAKER FINISHERS!

Immunology Training Grant gets renewal

The Immunology Training Grant, with Kris Hogquist as PI, was just renewed by the National Institute of Allergy and Infectious Diseases for another five years.  This grant has funded immunology graduate students at the University of Minnesota Medical School since 1989 or 28 years of continuous funding.  

Nelson receives Cancer Center Grant

Andy Nelson is a recipient of a $50,000 Masonic Cancer Center Translational Working Group Grant.  His proposal was “Creation of a Tissue Microarray”, a Breast Cancer Translational Working Group Pilot project.

There be twins!

Sarah and Scott Williams are the happy (exhausted) parents of twin boys, Evan Gregory and Bennett Alan, born Friday, July 28.  Mom and babies are all healthy and doing well.  See photo below.

PA receives recognition

Meghan Pickard, pathologists’ assistant, recently received an Extraordinary U+ award.  Pickard was recognized for going above and beyond to help during a period of short staffing and keeping a positive attitude while doing it.  These awards are given through the U+ program at University of Minnesota Physicians.

Meet our new faculty

THIS WEEK there will be an informal reception for new faculty on Wednesday, August 16 at 3:00 pm in the Bell, D175 Mayo.

Faculty publish

Murugan P, Rao P, Tamboli P, Czerniak B, Guo CC. Primary Ewing Sarcoma / Primitive Neuroectodermal Tumor of the Kidney: A Clinicopathologic Study of 23 Cases. Pathol Oncol Res. 2017 Apr 20. doi: 10.1007/s12253-017-0228-0. [Epub ahead of print] PubMed PMID: 28429277  

Gauer JL and Jackson JB.  The association of USMLE Step 1 and Step 2 CK scores with residency match specialty and location. Medical Education Online, 22:1, 1358579. Doi: 10.1080/10872981.2017.1358579. http://www.tandfonline.com/doi/full/10.1080/10872981.2017.1358579

Read updates from the Dean’s office

  • ISH/Gallagher consultants are on site interviewing department heads, UMP leadership and center directors about compensation and operations.  Both Dr. Furcht and Kathleen Dockter met with the consultants.  This addresses the Board of Regents concerns about the alignment between UMP and the Medical School.
  • Discussions continue to be positive between the U’s negotiating team (which includes President Kaler) and Children’s on a potential partnership.  
  • The Women in Leadership Committee is collecting salary equity data and also focusing on professional development opportunities for women.

Mark your calendars

  • John Eckfeldt’s retirement reception is scheduled for Wednesday, August 30 at 4:00 pm on the Campus Club Terrace in Coffman Union.  Faculty, please RSVP to Jean Kurata at jkurata@umn.edu

Medical School offers the P3 program to help grant writing

Assistant professors and early-career associate professors are encouraged to apply to the AHC Proposal Preparation Program (P3) being offered this fall.  This program provides interactive, peer grant writing group support for early-career faculty to help prepare for their first K-or R-series NIH grant proposal.  Deadline is August 18.  For more information look here.  https://hub.med.umn.edu/faculty-affairs/faculty-development-advancement-opportunities/grant-writing

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Williams twins

 

Publication date: 
Monday, August 14, 2017

LMP News, July 31, 2017

Hecht receives Dean’s recognition

Stephen Hecht, professor in LMP and the Masonic Cancer Center, was recently selected to give the fifth annual Dean’s Distinguished Research Lectureship.  Hecht will share the award with Dorothy Hatsukami, professor in the Department of Psychiatry.  Hecht, the Wallin Land Grant Professor of Cancer Prevention, researches the properties of carcinogens in tobacco products.  The Dean’s Distinguished Research Lectureship will be celebrated on Thursday, October 26 from 4:30 – 6:30pm in the Best Buy Theater of Northrop Auditorium.  

Dermatopathologist to join LMP

Alessio Giubellino, MD, PhD accepted our offer to join our dermatopathology service.  Giubellino completed a fellowship in dermatopathology at the University of Miami.  He did his residency at the NIH and NCI in anatomic pathology.  Giubellino received his MD from the University of Turin School of Medicine in Italy and a PhD in experimental and molecular oncology at the University of Pisa.  Besides clinical service, Giubellino will also develop a research program related to cancer.  

Hupp nominated for Resident Leadership Academy

Meghan Hupp, PGY-2 resident, was nominated to the Cohort 3 of the Resident Leadership Academy by Department Head Leo Furcht.  The aims of the year-long program are to teach skills relevant to organizational leadership engage residents in institutional goals and priorities and invest in the development of residents who have the potential to be future leaders at the U of M.

Salary Savings awarded

This is the second year that LMP has awarded salary savings funds to faculty who have covered more than 50% of their University compensation through grants.  Five faculty will receive discretionary funds.  Awards range from $10,000 to $20,000 and are made annually based on July 1 funded effort. Faculty who are hold chairs or professorships are not eligible for the program. 

Clark moves to Mayo

Neuropathologist Brent Clark moved his office last Friday from the basement of Diehl Hall to C515 Mayo where he will actually have a window.   The new suite of offices will house neuropathology and dermatopathology faculty and includes a space for residents while on service.  

Two new faculty start in LMP

Joe Rudolf, assistant professor, started his orientation to the department on July 24.  Rudolf’s position will be associate chief medical informatics officer for LMP and the Fairview Health Services.  He has two offices:  D217 Mayo and 150A at 323 Stinson Blvd NE, Minneapolis.  His e-mail is jrudolf@umn.edu.  His University phone is 612-626-2607 and his Fairview phone is 612-672-7122.   Margaret “Maggie” Flanagan, assistant professor, starts today, July 31.  Flanagan will be on neuropathology service in C514-1 Mayo.  Her phone number on service is 612-624-6563.  Her academic office will be in the Wallin Medical Biosciences Building in C514-1 WMBB.  Flanagan’s e-mail is mflanaga@umn.edu and her academic phone number is 612-625-6419. 

Medical School offers the P3 program to help grant writing

Assistant professors and early-career associate professors are encouraged to apply to the AHC Proposal Preparation Program (P3) being offered this fall.  This program provides interactive, peer grant writing group support for early-career faculty to help prepare for their first K-or R-series NIH grant proposal.  Deadline is August 18.  For more information look here.  https://hub.med.umn.edu/faculty-affairs/faculty-development-advancement-opportunities/grant-writing

Time is running out to support our LMP faculty Chainbreaker riders

NINE LMP faculty will ride in the Chainbreaker Ride for Cancer Research August 11-13:  Scott Dehm, Michael Farrar, Bartosz Grzywacz, Brooks Jackson, Tucker LeBien, Danni Li, Christopher Pennell, Kaylee Schwertfeger and Yoji Shimizu.  Please donate and support these riders at https://chainbreakerride.org/riders/  You can do a search by their names.   It takes less than two minutes to donate!    All funds will go to cancer research at the U of M. 

Faculty publish

Cannon CM, Trembley JH, Kren BT, Unger GM, O’Sullivan MG, Cornax I, Modiano JF, Ahmed K: Therapeutic targeting of protein kinase CK2 gene expression in feline oral squamous cell carcinoma: A naturally occurring large animal model of head and neck cancer. Human Gene Therapy Clinical Development, Volume 28, Number 2, 2017. DOI: 10.1089/humc.2017.008 

Mark your calendars

  • There will be an informal reception for new faculty on Wednesday, August 16 at 3:00 pm in the Bell, D175 Mayo.
  • John Eckfeldt’s retirement reception is scheduled for Wednesday, August 30 at 4:00 pm on the Campus Club Terrace in Coffman Union.

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, July 31, 2017

LMP News, July 17, 2017

Mroz is first of new faculty on site

Pawel Mroz, assistant professor, moved into his office in D222 Mayo on Monday, July 10.  Mroz will be on service in Molecular Diagnostics and Hematopathology.  His e-mail is pmroz@umn.edu and phone number is 612-624-6168.  Stop by and say hello. (See photo attached)

Barnes residency grant funded

Aaron Barnes, PGY-2, was awarded $2,500 from the department for his grant application “Rapid Antibiotic Resistance Detection via Quantitative MALDI-TOF Mass Spectrometry.”  Working with Patricia Ferrieri, Barnes will attempt to use MALDI-TOF mass spectrometry for rapid identification of antibiotic resistance gene expression to reduce the TAT from days to hours. 

ALRT hires a financial analyst

Rachel Brisson starts in mid- August as the new ALRT financial analyst providing support to Laboratory Medicine and Pathology as well as two other ALRT departments. Brisson will calculate the wRVU reports for the department, among other financial responsibilities. She most recently worked at University of Minnesota Physicians but also has experience at Hamline University, the U’s Office of Technology Commercialization, and the Commercial Associations of Realtors.  Brisson will have an office on 760 Mayo in the ALRT Center. 

Time is running out to support our LMP faculty Chainbreaker riders

Eight LMP faculty will ride in the Chainbreaker Ride for Cancer Research August 11-13:  Scott Dehm, Michael Farrar, Bartosz Grzywacz, Brooks Jackson, Danni Li, Christopher Pennell, Kaylee Schwertfeger and Yoji Shimizu.  Please donate and support these riders at https://chainbreakerride.org/riders/  You can do a search by their names.   It takes less than two minutes to donate!    All funds will go to cancer research at the U of M. 

Read updates from the Dean’s office

  • The Medical School’s CTSI application received a “fantastic” score of 20; there is optimism about funding.  The School plans to open a one stop Clinical Research Services Center on 2PWB sometime in the near future.
  • The University Foundation raised an all-time record $78 million in donations for the Medical School.
  • Negotiations will continue on a renewal of the MHealth agreement.  Our goal is to integrate our three part mission and provide world-class destination services for both complex and primary care conditions.
  • Lewis-Burke consultants, who lobby in Washington, are employed by the U to review our research portfolio and help us make connections to other funding agencies.  If you want to talk with them directly, contact Emily Lawrence, at emilyl@umn.edu 

Faculty publish

Steffen BT, Bielinski SJ, Decker PA, Berardi C, Larson DB, Pankow JS, Michos ED, Hanson NQ, Herrington DM, Tsai MY. Low high-density lipoprotein cholesterol and particle concentrations are associated with greater levels of endothelial activation markers in Multi-Ethnic Study of Atherosclerosis participants. J Clin Lipidol. 2017 Jun 13. Pii: S1933-2874(17)30347 -1.doi: 10.1016/j.jacl.2017.05.018. (EPub ahead of print).

Bielinski SJ, Berardi C, Decker PA, Larson NB, Bell EJ, Pankow JS, Sale MM, Tang W, Hanson NQ, Wassel CL, de Andrade M, Budoff MR, Polak JF, Sicotte H, Tsai MY. Hepatocyte  growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease. Heart.2017 Jun1. Pii:heartjnl-2016-310450. Doi:10.1136/heartjnl-2016-310450. (EPub ahead of print) 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Pawel Mroz

Publication date: 
Monday, July 17, 2017

LMP News, July 5, 2017

Meet and greet the new residents and fellows

Stop by TODAY from 3-4:30 to welcome our new residents and fellows in the Bell Conference room (May D175).  Light refreshments will be served.

Jameson is co-I on Masonic Cancer Center grant

Steve Jameson and Erin Dickerson, Department of Veterinary Clinical Sciences, received a $50,000 Brainstorm Award from the Masonic Cancer Center for their proposal “Using adrenergic receptor antagonists to inhibit sarcoma growth and enhance T cell responses.”   

AP hires new research coordinator

Dave Ankario starts on Monday, July 10, as the new research coordinator in the Division of Anatomic Pathology.  Ankario has lengthy experience working in different research roles at the University including Surgery’s Division of Solid Organ Transplant and Jeff Miller’s lab in the Cancer Center.  His office is in 203 DVCCRC and his phone is 612-626-7645.  Ankario will report to Faqian Li. 

Killeen makes “Top Doc” list

Mpls.St.Paul Magazine released the 21st annual “Top Doctors” edition which features physicians recognized by their peers in their field.  Tony Killeen made the list for 2017 in the category of Pathology.  Over 100 UMPhysicians doctors made the list.  Killeen also made the list in 2016.

Regents approve compensation increase 2017-18

Faculty, professional and academic salary and civil service employees are eligible for an average 2% increase for fiscal year 20217-18.  Our pay plans are being approved and increases are expected to show up on paychecks in July.

It is time to donate to your LMP faculty Chainbreaker riders

Eight LMP faculty will ride in the Chainbreaker Ride for Cancer research August 11-13:  Scott Dehm, Michael Farrar, Bartosz Grzywacz, Brooks Jackson, Danni Li, Christopher Pennell, Kaylee Schwertfeger and Yoji Shimizu.  Please donate and support these riders at https://chainbreakerride.org/riders/  You can do a search by their names.   It takes less than two minutes to donate!   You can still sign up to be a rider!  To register for this event go to https://chainbreakerride.org/register/   All funds will go to cancer research at the U of M.  Let us know if you register so we can add you to our list.

Des Burke passed away

We lost an emeritus faculty member recently.  Des Burke was one of a number of graduates of the National University of Ireland School of Medicine in Galway who contributed to our pathology teaching programs.  He completed a fellowship in clinical pathology here at the U of M (he overlapped in training with John Crosson) and for fifteen years was an adjunct professor at the U and pathologist at Mt. Sinai Hospital.  Crosson points out that Burke, along with Pat Ward and Chuck Horwitz, established the laboratory medicine course at the Medical School.  Burke moved on to an academic career first at SUNY Stony Brook and later as vice-chair of pathology at the Cornell Medical Center.

UMP offers a Roth 401(k) option

Effective July 1 a new Roth 401(k) option is available if you participate in the UMP retirement savings and 401(k) plan.  The contribution is after-tax so you will not pay taxes on distributions or earnings.  See attachment below.  

Faculty publish

Buckley, S.A., Wood, B. L., Othus, M, Hourgain, C.S., Ustun, C., Linden, M. A., DeFor, T. E., Malagola, M., Anthias, C., Valkova, V., Kanakry, C. G., Gruhn, B, Buccisano, F., Devine, B. E., and Walte, R. B.  Measurable (“minimal”) residual disease prior to hematopoietic cell transplantation in acute myeloid leukemia: a meta-analysis.  Hematologica  2017 Mayhttps://www.ncbi.nlm.nih.gov/pubmed/28126965

Baughn, L. B., Mitra, A., Van Ness, B. G., Noble, K., Sachs, Z, and Linden M. A. Phenotypic and functional characterization of a bortezomib resistant multiple myeloma cell line by flow and mass cytometry.  Leukemia and Lymphoma 2017 Aug:58(8) 1931-1940, Epub https://www.ncbi.nlm.nih.gov/pubmed/27981867

Baughn, L. B., and Linden, M. A.  Standardization of minimal residual disease testing in multiple myeloma.  Journal of Applied Laboratory Medicine DOI: 10.1373/jalm.2016.020883 Published May 2017  http://jalm.aaccjnls.org/content/early/2017/05/29/jalm.2016.020883

Rashidi A, Nelson ACLinden MA, Weisdorf DJ, Dolan MM, Ustun C. Genomics of clonal evolution in a case of essential thrombocythemia.Leuk Lymphoma. 2017 Jun 11:1-4. doi: 10.1080/10428194.2017.1337113. [Epub ahead of print] PMID: 28604261

Lou E, D'Souza D, Nelson ACTherapeutic Response of Metastatic Colorectal Cancer Harboring a KRAS Missense Mutation After Combination Chemotherapy With the EGFR Inhibitor Panitumumab. J Natl Compr Canc Netw. 2017 Apr;15(4):427-432. PMID:28404754

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

PDF icon roth_401k_participant_brochure_fr_pd_1_.pdf

 

Publication date: 
Wednesday, July 5, 2017

LMP News, June 19, 2017

Have you donated yet to our LMP faculty Chainbreaker riders??

Eight LMP faculty will ride in the Chainbreaker Ride for cancer research August 11-13:  Scott Dehm, Michael Farrar, Bartosz Grzywacz, Brooks Jackson, Danni Li, Christopher Pennell, Kaylee Schwertfeger and Yoji Shimizu.  Please donate and support these riders at https://chainbreakerride.org/riders/  You can do a search by their names.   It takes less than two minutes to donate!   You can still sign up to be a rider!  To register for this event go to https://chainbreakerride.org/register/   All funds will go to cancer research at the U of M.  Let us know if you register so we can add you to our list.  FLASH:  Chainbreaker lunch rally on Diehl Hall Plaza, Thursday, June 22 @11:30 a.m.

Pankratz named chair of national committee

Nathan Pankratz was named the new chair of the Structural Variation Working Group for NHLBI's TOPMed program. This national group is responsible for calling deletions, duplications, inversions and translocations for 120,000 study participants with deep whole genome sequencing data. These variants will then be correlated with disease outcomes and related traits to generate new understanding of the biological processes that underlie heart, lung, blood and sleep disorders.

Pennell reaches out to community on understanding cancer

Chris Pennell recently addressed community members at the Northside’s Cora McCorvey Health and Wellness Center about cancer and cancer research.  The purpose of the talk is to communicate the concepts of cancer to a wider population and connect the community back to the University’s research.  Pennell is associate director for education and community engagement in the Cancer Center.

Johnson named associate director of residency program

Effective July 1, Andy Johnson will take over the role of associate director of the residency program.  Johnson will work with Michelle Dolan as part of the leadership team that provides oversight to our clinical training programs.  We want to thank Emil Racila for his outstanding efforts; he will continue to serve on the RAFT committee.

Program names 2017-18 Chief Residents

The new chief residents are Jessica Gruenberg and Victor Santiago, both will be PGY-4 residents this summer.  Gruenberg is a graduate of the University of Minnesota Medical School; Santiago is a graduate of Universidad Autonoma de Guadalajara Facultad de Medicina. 

Faculty named Top Teachers

Each year the residents in our AP/CP pathology training program vote for the top teachers in anatomic pathology (AP) and clinical pathology (CP).  This year Amy Karger received the CP Teacher of the Year award and Tamera Lillemoe, adjunct assistant professor at Abbott-Northwestern received the AP Teacher of the Year award.  The honors were announced at LMP’s annual resident and fellow graduation dinner.

Compensation changes for 2017-18

Faculty and professional and academic salary recommendations were submitted to the Dean’s Office and UMPhysicians for approval on June 2.  Board of Regents votes on the University compensation plan on June 20.  Watch for a notification in the next few weeks.

Faculty publish

Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.Xia H, Gilbertsen A, Herrera J, Racila E, Smith K, Peterson M, Griffin T, Benyumov A, Yang L, Bitterman PB, Henke CA. J Clin Invest. 2017 May 22. pii: 90832. doi: 10.1172/JCI90832. [Epub ahead of print]

CD8αα intraepithelial lymphocytes arise from two main thymic precursors.Ruscher R, Kummer RL, Lee YJ, Jameson SC, Hogquist KA. Nat Immunol. 2017 May 22. doi: 10.1038/ni.3751. [Epub ahead of print]  PMID:28530714

Vahidi S, Amin K, Stewart, J 3rd, Laryngeal Chondrosarcoma mimicking medullary thyroid carcinoma on fine needle aspiration cytology: A case report of a diagnostic pitfall, EARLY VIEW Online Diagn. Cytopathol. June 2017 http://onlinelibrary.wiley.com/doi/10.1002/dc.23764/full

Sekulic M, Amin K, Mettler, T, Miller LK, Mallery, S, Stewart J 3rd, Pancreatic involvement by metastasizing neoplasms as determined by endoscopic ultrasound-guided fine needle aspiration: a clinicopathologic characterization, Diagn. Cytopathol. 45(5)pp 418–425, May 2017 https://www.ncbi.nlm.nih.gov/pubmed/28205397

Successful treatment of pure red cell aplasia because of ABO major mismatched stem cell transplant.  Sackett K, Cohn CS, Fahey-Ahrndt K, Smith AR, Johnson AD. J Clin Apher. 2017 May 24. doi: 10.1002/jca.21553. [Epub ahead of print] PMID:28543448

Campus club opens up its doors to all diners

Through the end of August, the Campus Club is open to non-members from 4 to 7 pm, M-F.  Besides happy hours you can order off the dinner menu which includes some good looking hamburgers featured in a June 9 story by the Star Tribune https://goo.gl/dZTYI1

Publication date: 
Monday, June 19, 2017

LMP News, June 5, 2017

Eckfeldt to receive Medical School Faculty Mentor Award

John Eckfeldt has been named winner of the 2017 Medical School Carole J. Bland Outstanding Faculty Mentor Award. The award recognizes faculty who serve as role models, promote the professional development of others, and create a supportive, positive working environment.  It was created through the generosity of Bland’s family and friends to honor her and to underscore the commitment of the Medical School to promote mentoring among faculty.  The award will be presented at the Medical School Promotion and Tenure reception on Thursday, June 15 at 4:30 p.m. at the Weisman Art Museum. For full story visit our website at https://www.pathology.umn.edu/

Support LMP faculty in Chainbreaker event

As of today seven LMP faculty will ride in the Chainbreaker Ride for Cancer research August 11-13:  Danni Li, Scott Dehm, Bartosz Grzywacz, Yoji Shimizu, Brooks Jackson, Kaylee Schwertfeger and Christopher Pennell.  Please donate and support these riders at https://chainbreakerride.org/riders/  You can do a search by their names.   It literally takes 2 minutes to donate!   You can still be a rider!  To register for this event go to https://chainbreakerride.org/register/   All funds will go to cancer research at the U of M. 

Ernst award winners announced

Over 17 abstracts and 7 papers were submitted for consideration of this year’s Ernst Award.  The 2017 winners are:

  • Best CP non-fellow Abstract - Amy Beckman, “Evaluation of an Automated PCR/Nucleic Acid Microarray-Based Platform for Enteric Pathogen Testing” Mentor: Pat Ferrieri, oral presentation at ACLPS 2017
  • Best AP non-fellow Abstract - Maryam Shahi, “Correlation of Cytomorphologic Features and Mutational Profile of Thyroid Nodules with Indeterminate Cytologic Diagnosis” Mentor: Khalid Amin, oral presentation at USCAP 2017
  • Best fellow Abstract - Lisa Johnson, “Comparison of LeadCare Ultra® to ICP-MS as an initial screen for blood lead levels." Mentor: Amy Karger. Poster presentation at AACC.
  • Best Paper - Miro Sekulic - "Kidney Biopsy Yield An Examination of Influencing Factors."  Mentor: Gretchen Crary (HCMC).  Published in the American Journal of Surgical Pathology

The Ernst award was established in 1977 by Thomas and Freda Turner to honor Kenneth F. Ernst who was Turner’s colleague and mentor while serving in the Army.  Ernst was a graduate of the U of M Medical School and specialized in pathology.

Ovarian Cancer Early Detection Program featured

Amy Skubitz is the director of the Ovarian Cancer Early Detection Program recently featured in a May issue of Mpls.StPaul magazine.  The program was cited for research into the discovery and validation of biomarkers for the early detection of ovarian cancer.  For more:  http://mspmag.com/health-and-fitness/empowering-a-change/   Related to this story, Skubitz also received a two year grant for $200,000 from the Minnesota Ovarian Cancer Alliance for her research on the validation of biomarkers for the early detection of ovarian cancer.

Thame is visiting scholar in hematopathology

Jennifer Thame, hematologist at the National Public Health Laboratory in Kingston, Jamaica will be a visiting scholar for three months in hematopathology funded through an award from the American Society of Hematology.  Thame will become a medical director of a new flow cytometry lab at her hospital on her return.  See her photo below with Bartosz Grzywacz in flow cytometry. 

Alumni receive award

Two LMP alumni, Jess Peterson and Charanjeet Sing, won the ASCP’s 40-under-forty award.  This program recognizes 40 ASCP members under the age of 40 for their achievements and leadership qualities that have an impact on our specialty.   Peterson was a molecular genetic pathology fellow from 2011-12 and Singh was an AP/CP resident and hematopathology fellow from 2009-2013.  Here is the link to the program https://www.ascp.org/content/40-under-forty

MPG Great Idea Awards are Due June 14

Division of Molecular Pathology and Genomics members are invited to submit applications for a Great Idea Award worth $5,000.  More information is on line at the MPG webpage. https://www.pathology.umn.edu/molecular-pathology-and-genomics  Decisions on the awards will be made at the MPG division meeting on June 21, noon-1:30 pm at the Campus Club. 

Research fund available for residents and fellows

Small research grants (maximum $2500) are available for residents and fellows. The next deadline is June 15.  A faculty committee reviews and awards the grants.  For more information go to this page on our website and review “Application Details”: https://www.pathology.umn.edu/residency-fellowships/residency/research-experience

Reminder:  Medical School offers publication workshop

The Path to Publication workshop will be offered by the Medical School on Monday, June 12 from 12:30 – 4:30 pm at the McNamara Alumni Center (Oak and Washington).  This is a really good workshop for faculty with minimal to moderate experience in writing for peer-reviewed journals.  Register here:  https://goo.gl/tvU1AA

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Jennifer & Bartok

Publication date: 
Monday, June 5, 2017

LMP News, May 22, 2017

Tsai hits double on grants

Mike Tsai recently received funding for two grants.  One is a pilot study funded by NIH-NICHD on Pilot Extraction of RNA from B Well Mom Samples in RNALATER for $43,785.  The second is a two year grant focused on “Genetic Factors of Birth Defects – Genomics Testing” for $781,728.

Karger authors blog on Ebola

Oxford University Press invited Amy Karger to write a blog post for lay people related to her recent Ebola publication (see April 24 LMP e-newsletter).  Here is the link:  https://blog.oup.com/2017/05/preparing-clinical-laboratories-future-pandemics/?utm_source=twitter&utm_medium=oupacademic&utm_campaign=oupblog

Pathologist’s assistant joins staff in Anatomic Pathology

Nea Moyer started her new position as a pathologist’s assistant last Monday.  Moyer is a graduate of Tulane University and received her M.S. Pathologist’s Assistant degree from the University of Maryland-Baltimore in May 2015.  Moyer is no stranger to Minneapolis; she worked for the anatomy request program for several years.  Her most recent position was at the Puget Sound Institute of Pathology.  Her e-mail is nmoyer10@umphysicians.umn.edu. Welcome Nea.

ISO Technical Committee is on campus this week

Tony Killeen is host for a meeting of the International Organization for Standardization (ISO) Technical Committee 212 (work group 2) at the U of M this week.  The committee is involved with traceability in laboratory medicine.  Delegates are expected from the US, Germany, Australia, and France.  For more information on ISO/TC212 visit:  https://www.iso.org/committee/54916.html  It is quite the honor to host this meeting so Kudos to Killeen.

Khalifa to judge surgeons

The Department of Surgery holds its Research Day Poster Session on May 23 from 7-9 am on 11 PWB.  Mahmoud Khalifa will be one of the judges for the event and will help select the winners of the best basic and clinical research presentations.  

Faculty publish

Levy E, Saenger AK, Steffes MW, Delvin E. Pediatric Obesity and Cardiometabolic Disorders: Risk Factors and Biomarkers.  EJIFCC. 2017 Mar 8;28(1):6-24.
https://www.ncbi.nlm.nih.gov/pubmed/28439216

Saenger AK, Korpi-Steiner N. Advances in Cardiac Biomarkers of Acute Coronary Syndrome. Adv Clin Chem. 2017;78:1-58. doi: 10.1016/bs.acc.2016.07.001. 
https://www.ncbi.nlm.nih.gov/pubmed/28057184

Manish Kohli, Yeung Ho, David W. Hillman, Jamie L. Van Etten, Christine Henzler, Rendong Yang, Jamie M. Sperger, Yingming Li, Elizabeth Tseng, Ting Hon, Tyson Clark, Winston Tan, Rachel E. Carlson, Liguo Wang, Hugues Sicotte, Ho Thai, Rafael Jimenez, Haojie Huang, Peter T. Vedell, Bruce W. Eckloff, Jorge F. Quevedo, Henry C. Pitot, Brian A. Costello, Jin Jen, Eric D. Wieben, Kevin A.T. Silverstein, Joshua M. Lang, Liewei Wang, and Scott M. Dehm.  Androgen receptor variant AR-V9 is co-expressed with AR-V7 in prostate cancer metastases and predicts abiraterone resistance.  Clin Cancer Res, 2017 May 4.  pii: clincanres.0017.2017. doi: 10.1158/1078-0432.CCR-17-0017. [Epub ahead of print]  https://www.ncbi.nlm.nih.gov/pubmed/28473535

MPG Great Idea Awards are Due June 14

Division of Molecular Pathology and Genomics members are invited to submit applications for a Great Idea Award worth $5,000.  More information is on line at the MPG webpage. https://www.pathology.umn.edu/molecular-pathology-and-genomics  Decisions on the awards will be made at the MPG division meeting on June 21, noon-1:30 pm at the Campus Club.

Research fund available for residents and fellows

Small research grants (maximum $2500) are available for residents and fellows. The next deadline is June 15.  A faculty committee reviews and awards the grants.  For more information go to this page on our website and review “Application Details”: https://www.pathology.umn.edu/residency-fellowships/residency/research-experience

Luquette is co-author on poster

Mark Luquette was a co-author of a poster presented at the annual meeting of the Minnesota Chapter of the American Academy of Pediatrics (MNAAP) in Bloomington recently.  The poster, “Under pressure: Tension Pneumothorax with evolving cysts in an infant with RSV”, won First Place – Resident Clinical Vignette Poster Competition.   Co-authors included Ariel Stein, Helena Molero, Donavon Hess and Michael Pitt.

Reminder:  Medical School offers publication workshop

The Path to Publication workshop will be offered by the Medical School on Monday, June 12 from 12:30 – 4:30 pm at the McNamara Alumni Center (Oak and Washington).  This is a really good workshop for faculty with minimal to moderate experience in writing for peer-reviewed journals.  Register here:  https://goo.gl/tvU1AA

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, May 22, 2017

LMP News, May 8, 2017

Barnes abstract scores in top three

Aaron Barnes’ ACLPS abstract  “Enterococcus faecalis colonizes and forms persistent biofilm microcolonies on the undamaged endothelial surface in a rabbit endovascular infection model,” was scored as one of the top clinical/translational science abstracts submitted for the annual ACLPS meeting and is eligible for the Paul E. Strandjord Young Investigator Award with Distinction.   Barnes will find out at the ACLPS meeting if he is one of the winners of a cash award.  

NIH cap will free up funds for early career investigators; impact likely in September 

The NIH just announced a major policy shift that will cap the number of grants an investigator can hold (equivalent to 3 NIH R01 Grants).  The freed up funds will provide more funding for early-career scientists and those researchers struggling to keep their labs afloat.  Follow this link for the full NIH announcement.  Note that this policy will likely be implemented in time for September grant applications. https://goo.gl/ghajfV

Chadburn is visiting professor in hematopathology on Monday, May 15

Amy Chadburn, professor of pathology at Weill Cornell Medical Center, visits the Division of Hematopathology on Monday, May 15.  Chadburn is a leader in diagnostic pathology with expertise in lymphoproliferative disorders associated with immunodeficiency.  She will be giving a slide seminar for LMP residents and fellows at 9:00 am.   If anyone would like to meet with Dr. Chadburn, please contact Michael Linden at linde013@umn.edu  See her profile at https://weillcornell.org/achadburn

Balfour appears on Access Minnesota 

Hank Balfour recently participated in an interview on Access Minnesota broadcasted by 43 stations statewide. He discussed the potential importance of a vaccine to prevent mono, caused by Epstein-Barr virus (EBV), and the implication that EBV vaccine could reduce the number of cases of multiple sclerosis, Hodgkin disease, and other lymphomas. On April 25, he spoke about the EBV vaccine to the Twin Cities Broadcasters Ascertainment Group’s a quarterly meeting for members of Twin Cities radio and TV stations.

Linden named to committee

Michael Linden was invited to serve on the Myeloma Committee for the Alliance in Clinical Trials for Oncology.  Though the committee is composed primarily of hematologists/oncologists, each committee has representation from one pathologist to guide laboratory based testing in clinical trial design/support.  In addition, Linden will also serve on the Alliance's Pathology committee.

Faculty publish

Powell,DE and Wallschlaeger, A  Making sense of the milestones: Entrustable professional activities for pathology. Human Pathology (2017) 62, 8-12.

Buchanan, P.C., Boylan, K.L.M., Walcheck, B., Heinze, R., Geller, M.A., Argenta, P.A., and Skubitz, A.P.N.  (2017)  Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17. Journal of Biological Chemistry 292(15):6339-6351.

Undergraduate wins UROP award for work in Balfour lab

Lauren Duval, a U of M sophomore, was awarded an Undergraduate Research Opportunities Program (UROP) grant for her project, "When is a Patient with Mononucleosis Most Infectious?"  with Hank Balfour.  This is the 11th UROP award for the Balfour lab, which encourages undergraduate participation in research focused on Epstein-Barr virus diseases

2017’s final Research Forum features Kaylee Schwertfeger

This academic year’s final research forum this Thursday, May 11, will feature Kaylee Schwertfeger who will discuss her new grant  “Contributions of FGFR-mediated tumor-stromal interactions to breast cancer growth and progression. “  As usual the forum will meet in the Dale Shephard room at the Campus Club starting at 5:00 p.m.  Light refreshments will be provided. 

Medical school offers publication workshop

The Path to Publication workshop will be offered by the Medical School on Monday, June 12 from 12:30 – 4:30 pm at the McNamara Alumni Center (Oak and Washington).  This is a really good workshop for faculty with minimal to moderate experience in writing for peer-reviewed journals.  Register here:  https://goo.gl/tvU1AA

Last chance to RSVP for LMP’s annual resident and fellow graduation dinner at the Campus Club on Wednesday, May 31.  Social hour starts at 5:00 with dinner at 5:30.  RSVP by May 18 to Gail Rosenbaum at rosen018@umn.edu

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, May 8, 2017

LMP News, April 24, 2017

ACLPS accepts residents’ abstracts

Three residents had abstracts accepted for the 2017 Annual Meeting of the Academy of Clinical Physicians and Scientists (ACLPS) to be held at Yale University in mid-June.  Amy Beckman’s submission “Evaluation of an automated PCR/nucleic acid microarray-based platform for enteric pathogen testing” was accepted for oral presentation and Thomas Gniadek’s abstract “Retrospective comparison between HLA-match and non-binary platelet crossmatch” was accepted for poster presentation.  Timothy Moss’s abstract “Whole exome sequencing in disorders of sexual development: Is it worth the cost?” was selected to receive a Paul E. Strandjord Young Investigator Award.  Strandjord, who died in 2001, did his residency in internal medicine at the University of Minnesota in 1959.  He was appointed head of the clinical chemistry division and later associate director of clinical labs in the Department of Laboratory Medicine at the U of M.  In 1969 he became the founding chair of the University of Washington’s Department of Laboratory Medicine.

Flow conference is a success

The second annual Twin Cities regional flow cytometry conference was both engaging and successful.  Over 70 people attended, including pathologists, technologists and pathology trainees.  The conference, hosted by LMP, received generous financial support from the Upper Midwest Flow Cytometry Users Group (UMFUG), six corporate vendors and individual donors.  Attendees traveled from as far north at Fargo, ND and as far south as Kingston, Jamaica.  If you would like to speak at the 2018 spring meeting or make a donation, please contact Michael Linden (linde013@umn.edu).  See conference photo attached.

Karger named to committee

Amy Karger was recently selected to serve as a contributor on the Clinical and Laboratory Standards Institute (CLSI) Document Development Committee on Capillary Blood Specimen Collection.  CLSI develops clinical and laboratory practice guidelines that are used worldwide.

Hats off to our clinical laboratory staff on Lab Week (April 23-29)

This week marks the annual Medical Laboratory Professionals Week to promote public understanding of and appreciation of the work of some 300,000 lab staff nationwide.  Take a moment this week to show your appreciation to our UMMC staff for their work in support of our clinical mission.

Register your international trip

The University wants you to register your paid international University travel with the University’s global Travel Program.   The two main goals of the policy are to (1) provide pre-departure assistance and information to faculty/staff and (2) to know where faculty/staff are located around the globe in the event of an emergency so that the University can more effectively provide assistance and coordinate help.  An online form is available at http://global.umn.edu/travelregistry/

Stall is new adjunct assistant professor

Jennifer Stall, M.D. recently joined the staff at Allina Health.  She received her MD at Indiana University, completed a residency in AP/CP Pathology at the University of Michigan and did fellowships in GYN and surgical pathology at Mass General.  Residents will work with her when they rotate on GYN pathology at Allina.

Faculty publish

Cao J, Senn C, Castaneda P, Humphries S, Karger AB. Establishing a stand-alone laboratory dedicated to the care of patients with Ebola virus disease. Lab Med, 2017 Mar 13, doi: 10.1093/labmed/lmw072.

Karger also recorded a podcast about this article, which can be found here: 

https://ascpcdn.s3.amazonaws.com/media/podcasts/Ebola-Karger

Khalifa MA, Salama S, Vogel RI, Klein ME, Richter J, Pulver T, Mullany SA, Winterhoff B.  Assessment of the intraoperative consultation service rendered by general pathologists in a scenario where a well-defined decision algorithm is followed.  Am J Clin Pathol 2017;147:322-326

Barbera L, Gien L, Sutradhar R, Thomas G, Covens A, Elit L, Fyles A, Rakovitch E, Liu Y, Khalifa M. The added value of pathology review in vulva cancer: Results from a population based cohort study.  In J Gynecol Pathol 2017;36:107-110

Gien LT, Sutradhar R, Thomas G, Covens A, Elit L, Rakovitch E, Fyles A, Khalifa MA, Liu Y, Barbera L.  Does a groin node dissection in vulvar cancer affect groin recurrence and overall survival? Results from a population-based cohort study.  Gynecol Oncol 2017;144:318-323

RSVP for LMP’s annual resident and fellow graduation dinner

It’s not too early to send in your reservation for this annual event to recognize our trainees.  The dinner will be held at the Campus Club on Wednesday, May 31.  Social hour starts at 5:00 with dinner at 5:30.  RSVP by May 18 to Gail Rosenbaum at rosen018@umn.edu

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

UMFUG

 

 

Publication date: 
Monday, April 24, 2017

LMP News, April 10, 2017

Schwertfeger awarded two grants

Kaylee Schwertfeger is starting off spring with two new grants.  One is a NIH/NCI RO1 on the contributions of FGFR-mediated tumor-stromal interactions to breast cancer growth and progress.  The goal of this grant is to define the mechanisms through which FGFR enhances breast cancer growth and progression through modulating the tumor microenvironment.  Collaborators include Jim McCarthy, Andy Nelson, Mike Farrar and Rebecca LaRue. Schwertfeger also received funding from METAvivor on the development of immune-based strategies to enhance therapeutic targeting of metastatic breast cancer.  This project will try to determine the efficacy of combining STAT3 inhibitors with immune checkpoint blockade on metastatic breast cancer.  METavivor is a foundation that supports metastatic breast cancer awareness, research and support,

UMP benefit is available to common paymaster faculty

UMP offers a new program to provide incidental care for children or elder family members.  Called “Back-Up Care” by Bright Horizons the program provides access to back-up care for children in your home or in a center.  It also provides in-home care for adult/elder family members throughout the US and gives you access to other family support.  You can access up to 10 days per calendar year of family care.  Visit http://www.careadvantage.com/ump  or call 1-877-BH-CARES.   You should have been sent the user name and password in an e-mail addressed to you but call or email Hanna Bergquist if you need it (bergq064@umn.eduor 612-624-7115).   You will also need your UMP ID number for registration; if you don’t know your number Hannah can help.  

Birkenbach leaving in June

Mark Birkenbach, associate professor, is leaving the department at the end of June to take a position at Brown University and Lifespan Academic Medical Center.   A search for a transplant pathologist is underway.  

Pathology QI team mentioned in MHealth E3 publication

Paari Murugan, Jennifer Morocho and Dip Shukla were part of 16 teams who participated in Cohort Three of the U of M Health Quality Improvement Collaborative.  Recently they presented their final results on the project:  pathology processing of prostate biopsies: an innovative model for reducing cost, test time and improving diagnostic material.  

Powell is featured in article on three-year medical school curriculum

Deborah Powell, professor, was quoted in an article in Becker’s Hospital Review on her AAMC project, “Education in pediatrics across the continuum…”  The focus of the article was on whether medical school could be condensed into 3 years; the ACGME project is out to confirm this and possibly change the model for medical school education in the future. https://goo.gl/lx0Lcr   

Faculty publish

Katerndahl CDS, Heltemes-Harris LM, Willette MJL, Henzler CM, Frietze S, Yang, R, Schjerven H, Silverstein KAT, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheije, B, van Leeuwen FN, Muschen M, Kornblau SM, Farrar MA.  Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nature Immunology, published online 03 April 2017. Doi:10.1038/ni.3716 http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.3716.html

Trembley JH, Kren BT, Abedin MJ, Vogel RI, Cannon CM, Unger, GM, Ahmed K: CK2 Molecular Targeting —Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer. Pharmaceuticals 2017, 10, 25; doi:10.3390/ph10010025

Research coordinator search starts over

Last issue we announced that Nick Blank would start as the new research coordinator in the Division of Anatomic Pathology on April 3.  Unfortunately, Blank was involved in a serious boating accident and is unable to honor his commitment.  A new recruitment effort has started.

Reminder:  Next research forum is Thursday, April 13 at 5:00 pm in the Dale Shephard Room, Campus Club featuring Ameeta Kelekar “Metabolic reprogramming in cancer therapy and immunotherapy”

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, April 10, 2017

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