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LMP News, May 22, 2017

Tsai hits double on grants

Mike Tsai recently received funding for two grants.  One is a pilot study funded by NIH-NICHD on Pilot Extraction of RNA from B Well Mom Samples in RNALATER for $43,785.  The second is a two year grant focused on “Genetic Factors of Birth Defects – Genomics Testing” for $781,728.

Karger authors blog on Ebola

Oxford University Press invited Amy Karger to write a blog post for lay people related to her recent Ebola publication (see April 24 LMP e-newsletter).  Here is the link:  https://blog.oup.com/2017/05/preparing-clinical-laboratories-future-pandemics/?utm_source=twitter&utm_medium=oupacademic&utm_campaign=oupblog

Pathologist’s assistant joins staff in Anatomic Pathology

Nea Moyer started her new position as a pathologist’s assistant last Monday.  Moyer is a graduate of Tulane University and received her M.S. Pathologist’s Assistant degree from the University of Maryland-Baltimore in May 2015.  Moyer is no stranger to Minneapolis; she worked for the anatomy request program for several years.  Her most recent position was at the Puget Sound Institute of Pathology.  Her e-mail is nmoyer10@umphysicians.umn.edu. Welcome Nea.

ISO Technical Committee is on campus this week

Tony Killeen is host for a meeting of the International Organization for Standardization (ISO) Technical Committee 212 (work group 2) at the U of M this week.  The committee is involved with traceability in laboratory medicine.  Delegates are expected from the US, Germany, Australia, and France.  For more information on ISO/TC212 visit:  https://www.iso.org/committee/54916.html  It is quite the honor to host this meeting so Kudos to Killeen.

Khalifa to judge surgeons

The Department of Surgery holds its Research Day Poster Session on May 23 from 7-9 am on 11 PWB.  Mahmoud Khalifa will be one of the judges for the event and will help select the winners of the best basic and clinical research presentations.  

Faculty publish

Levy E, Saenger AK, Steffes MW, Delvin E. Pediatric Obesity and Cardiometabolic Disorders: Risk Factors and Biomarkers.  EJIFCC. 2017 Mar 8;28(1):6-24.
https://www.ncbi.nlm.nih.gov/pubmed/28439216

Saenger AK, Korpi-Steiner N. Advances in Cardiac Biomarkers of Acute Coronary Syndrome. Adv Clin Chem. 2017;78:1-58. doi: 10.1016/bs.acc.2016.07.001. 
https://www.ncbi.nlm.nih.gov/pubmed/28057184

Manish Kohli, Yeung Ho, David W. Hillman, Jamie L. Van Etten, Christine Henzler, Rendong Yang, Jamie M. Sperger, Yingming Li, Elizabeth Tseng, Ting Hon, Tyson Clark, Winston Tan, Rachel E. Carlson, Liguo Wang, Hugues Sicotte, Ho Thai, Rafael Jimenez, Haojie Huang, Peter T. Vedell, Bruce W. Eckloff, Jorge F. Quevedo, Henry C. Pitot, Brian A. Costello, Jin Jen, Eric D. Wieben, Kevin A.T. Silverstein, Joshua M. Lang, Liewei Wang, and Scott M. Dehm.  Androgen receptor variant AR-V9 is co-expressed with AR-V7 in prostate cancer metastases and predicts abiraterone resistance.  Clin Cancer Res, 2017 May 4.  pii: clincanres.0017.2017. doi: 10.1158/1078-0432.CCR-17-0017. [Epub ahead of print]  https://www.ncbi.nlm.nih.gov/pubmed/28473535

MPG Great Idea Awards are Due June 14

Division of Molecular Pathology and Genomics members are invited to submit applications for a Great Idea Award worth $5,000.  More information is on line at the MPG webpage. https://www.pathology.umn.edu/molecular-pathology-and-genomics  Decisions on the awards will be made at the MPG division meeting on June 21, noon-1:30 pm at the Campus Club.

Research fund available for residents and fellows

Small research grants (maximum $2500) are available for residents and fellows. The next deadline is June 15.  A faculty committee reviews and awards the grants.  For more information go to this page on our website and review “Application Details”: https://www.pathology.umn.edu/residency-fellowships/residency/research-experience

Luquette is co-author on poster

Mark Luquette was a co-author of a poster presented at the annual meeting of the Minnesota Chapter of the American Academy of Pediatrics (MNAAP) in Bloomington recently.  The poster, “Under pressure: Tension Pneumothorax with evolving cysts in an infant with RSV”, won First Place – Resident Clinical Vignette Poster Competition.   Co-authors included Ariel Stein, Helena Molero, Donavon Hess and Michael Pitt.

Reminder:  Medical School offers publication workshop

The Path to Publication workshop will be offered by the Medical School on Monday, June 12 from 12:30 – 4:30 pm at the McNamara Alumni Center (Oak and Washington).  This is a really good workshop for faculty with minimal to moderate experience in writing for peer-reviewed journals.  Register here:  https://goo.gl/tvU1AA

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, May 22, 2017

LMP News, May 8, 2017

Barnes abstract scores in top three

Aaron Barnes’ ACLPS abstract  “Enterococcus faecalis colonizes and forms persistent biofilm microcolonies on the undamaged endothelial surface in a rabbit endovascular infection model,” was scored as one of the top clinical/translational science abstracts submitted for the annual ACLPS meeting and is eligible for the Paul E. Strandjord Young Investigator Award with Distinction.   Barnes will find out at the ACLPS meeting if he is one of the winners of a cash award.  

NIH cap will free up funds for early career investigators; impact likely in September 

The NIH just announced a major policy shift that will cap the number of grants an investigator can hold (equivalent to 3 NIH R01 Grants).  The freed up funds will provide more funding for early-career scientists and those researchers struggling to keep their labs afloat.  Follow this link for the full NIH announcement.  Note that this policy will likely be implemented in time for September grant applications. https://goo.gl/ghajfV

Chadburn is visiting professor in hematopathology on Monday, May 15

Amy Chadburn, professor of pathology at Weill Cornell Medical Center, visits the Division of Hematopathology on Monday, May 15.  Chadburn is a leader in diagnostic pathology with expertise in lymphoproliferative disorders associated with immunodeficiency.  She will be giving a slide seminar for LMP residents and fellows at 9:00 am.   If anyone would like to meet with Dr. Chadburn, please contact Michael Linden at linde013@umn.edu  See her profile at https://weillcornell.org/achadburn

Balfour appears on Access Minnesota 

Hank Balfour recently participated in an interview on Access Minnesota broadcasted by 43 stations statewide. He discussed the potential importance of a vaccine to prevent mono, caused by Epstein-Barr virus (EBV), and the implication that EBV vaccine could reduce the number of cases of multiple sclerosis, Hodgkin disease, and other lymphomas. On April 25, he spoke about the EBV vaccine to the Twin Cities Broadcasters Ascertainment Group’s a quarterly meeting for members of Twin Cities radio and TV stations.

Linden named to committee

Michael Linden was invited to serve on the Myeloma Committee for the Alliance in Clinical Trials for Oncology.  Though the committee is composed primarily of hematologists/oncologists, each committee has representation from one pathologist to guide laboratory based testing in clinical trial design/support.  In addition, Linden will also serve on the Alliance's Pathology committee.

Faculty publish

Powell,DE and Wallschlaeger, A  Making sense of the milestones: Entrustable professional activities for pathology. Human Pathology (2017) 62, 8-12.

Buchanan, P.C., Boylan, K.L.M., Walcheck, B., Heinze, R., Geller, M.A., Argenta, P.A., and Skubitz, A.P.N.  (2017)  Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17. Journal of Biological Chemistry 292(15):6339-6351.

Undergraduate wins UROP award for work in Balfour lab

Lauren Duval, a U of M sophomore, was awarded an Undergraduate Research Opportunities Program (UROP) grant for her project, "When is a Patient with Mononucleosis Most Infectious?"  with Hank Balfour.  This is the 11th UROP award for the Balfour lab, which encourages undergraduate participation in research focused on Epstein-Barr virus diseases

2017’s final Research Forum features Kaylee Schwertfeger

This academic year’s final research forum this Thursday, May 11, will feature Kaylee Schwertfeger who will discuss her new grant  “Contributions of FGFR-mediated tumor-stromal interactions to breast cancer growth and progression. “  As usual the forum will meet in the Dale Shephard room at the Campus Club starting at 5:00 p.m.  Light refreshments will be provided. 

Medical school offers publication workshop

The Path to Publication workshop will be offered by the Medical School on Monday, June 12 from 12:30 – 4:30 pm at the McNamara Alumni Center (Oak and Washington).  This is a really good workshop for faculty with minimal to moderate experience in writing for peer-reviewed journals.  Register here:  https://goo.gl/tvU1AA

Last chance to RSVP for LMP’s annual resident and fellow graduation dinner at the Campus Club on Wednesday, May 31.  Social hour starts at 5:00 with dinner at 5:30.  RSVP by May 18 to Gail Rosenbaum at rosen018@umn.edu

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, May 8, 2017

LMP News, April 24, 2017

ACLPS accepts residents’ abstracts

Three residents had abstracts accepted for the 2017 Annual Meeting of the Academy of Clinical Physicians and Scientists (ACLPS) to be held at Yale University in mid-June.  Amy Beckman’s submission “Evaluation of an automated PCR/nucleic acid microarray-based platform for enteric pathogen testing” was accepted for oral presentation and Thomas Gniadek’s abstract “Retrospective comparison between HLA-match and non-binary platelet crossmatch” was accepted for poster presentation.  Timothy Moss’s abstract “Whole exome sequencing in disorders of sexual development: Is it worth the cost?” was selected to receive a Paul E. Strandjord Young Investigator Award.  Strandjord, who died in 2001, did his residency in internal medicine at the University of Minnesota in 1959.  He was appointed head of the clinical chemistry division and later associate director of clinical labs in the Department of Laboratory Medicine at the U of M.  In 1969 he became the founding chair of the University of Washington’s Department of Laboratory Medicine.

Flow conference is a success

The second annual Twin Cities regional flow cytometry conference was both engaging and successful.  Over 70 people attended, including pathologists, technologists and pathology trainees.  The conference, hosted by LMP, received generous financial support from the Upper Midwest Flow Cytometry Users Group (UMFUG), six corporate vendors and individual donors.  Attendees traveled from as far north at Fargo, ND and as far south as Kingston, Jamaica.  If you would like to speak at the 2018 spring meeting or make a donation, please contact Michael Linden (linde013@umn.edu).  See conference photo attached.

Karger named to committee

Amy Karger was recently selected to serve as a contributor on the Clinical and Laboratory Standards Institute (CLSI) Document Development Committee on Capillary Blood Specimen Collection.  CLSI develops clinical and laboratory practice guidelines that are used worldwide.

Hats off to our clinical laboratory staff on Lab Week (April 23-29)

This week marks the annual Medical Laboratory Professionals Week to promote public understanding of and appreciation of the work of some 300,000 lab staff nationwide.  Take a moment this week to show your appreciation to our UMMC staff for their work in support of our clinical mission.

Register your international trip

The University wants you to register your paid international University travel with the University’s global Travel Program.   The two main goals of the policy are to (1) provide pre-departure assistance and information to faculty/staff and (2) to know where faculty/staff are located around the globe in the event of an emergency so that the University can more effectively provide assistance and coordinate help.  An online form is available at http://global.umn.edu/travelregistry/

Stall is new adjunct assistant professor

Jennifer Stall, M.D. recently joined the staff at Allina Health.  She received her MD at Indiana University, completed a residency in AP/CP Pathology at the University of Michigan and did fellowships in GYN and surgical pathology at Mass General.  Residents will work with her when they rotate on GYN pathology at Allina.

Faculty publish

Cao J, Senn C, Castaneda P, Humphries S, Karger AB. Establishing a stand-alone laboratory dedicated to the care of patients with Ebola virus disease. Lab Med, 2017 Mar 13, doi: 10.1093/labmed/lmw072.

Karger also recorded a podcast about this article, which can be found here: 

https://ascpcdn.s3.amazonaws.com/media/podcasts/Ebola-Karger

Khalifa MA, Salama S, Vogel RI, Klein ME, Richter J, Pulver T, Mullany SA, Winterhoff B.  Assessment of the intraoperative consultation service rendered by general pathologists in a scenario where a well-defined decision algorithm is followed.  Am J Clin Pathol 2017;147:322-326

Barbera L, Gien L, Sutradhar R, Thomas G, Covens A, Elit L, Fyles A, Rakovitch E, Liu Y, Khalifa M. The added value of pathology review in vulva cancer: Results from a population based cohort study.  In J Gynecol Pathol 2017;36:107-110

Gien LT, Sutradhar R, Thomas G, Covens A, Elit L, Rakovitch E, Fyles A, Khalifa MA, Liu Y, Barbera L.  Does a groin node dissection in vulvar cancer affect groin recurrence and overall survival? Results from a population-based cohort study.  Gynecol Oncol 2017;144:318-323

RSVP for LMP’s annual resident and fellow graduation dinner

It’s not too early to send in your reservation for this annual event to recognize our trainees.  The dinner will be held at the Campus Club on Wednesday, May 31.  Social hour starts at 5:00 with dinner at 5:30.  RSVP by May 18 to Gail Rosenbaum at rosen018@umn.edu

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

UMFUG

 

 

Publication date: 
Monday, April 24, 2017

LMP News, April 10, 2017

Schwertfeger awarded two grants

Kaylee Schwertfeger is starting off spring with two new grants.  One is a NIH/NCI RO1 on the contributions of FGFR-mediated tumor-stromal interactions to breast cancer growth and progress.  The goal of this grant is to define the mechanisms through which FGFR enhances breast cancer growth and progression through modulating the tumor microenvironment.  Collaborators include Jim McCarthy, Andy Nelson, Mike Farrar and Rebecca LaRue. Schwertfeger also received funding from METAvivor on the development of immune-based strategies to enhance therapeutic targeting of metastatic breast cancer.  This project will try to determine the efficacy of combining STAT3 inhibitors with immune checkpoint blockade on metastatic breast cancer.  METavivor is a foundation that supports metastatic breast cancer awareness, research and support,

UMP benefit is available to common paymaster faculty

UMP offers a new program to provide incidental care for children or elder family members.  Called “Back-Up Care” by Bright Horizons the program provides access to back-up care for children in your home or in a center.  It also provides in-home care for adult/elder family members throughout the US and gives you access to other family support.  You can access up to 10 days per calendar year of family care.  Visit http://www.careadvantage.com/ump  or call 1-877-BH-CARES.   You should have been sent the user name and password in an e-mail addressed to you but call or email Hanna Bergquist if you need it (bergq064@umn.eduor 612-624-7115).   You will also need your UMP ID number for registration; if you don’t know your number Hannah can help.  

Birkenbach leaving in June

Mark Birkenbach, associate professor, is leaving the department at the end of June to take a position at Brown University and Lifespan Academic Medical Center.   A search for a transplant pathologist is underway.  

Pathology QI team mentioned in MHealth E3 publication

Paari Murugan, Jennifer Morocho and Dip Shukla were part of 16 teams who participated in Cohort Three of the U of M Health Quality Improvement Collaborative.  Recently they presented their final results on the project:  pathology processing of prostate biopsies: an innovative model for reducing cost, test time and improving diagnostic material.  

Powell is featured in article on three-year medical school curriculum

Deborah Powell, professor, was quoted in an article in Becker’s Hospital Review on her AAMC project, “Education in pediatrics across the continuum…”  The focus of the article was on whether medical school could be condensed into 3 years; the ACGME project is out to confirm this and possibly change the model for medical school education in the future. https://goo.gl/lx0Lcr   

Faculty publish

Katerndahl CDS, Heltemes-Harris LM, Willette MJL, Henzler CM, Frietze S, Yang, R, Schjerven H, Silverstein KAT, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheije, B, van Leeuwen FN, Muschen M, Kornblau SM, Farrar MA.  Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival. Nature Immunology, published online 03 April 2017. Doi:10.1038/ni.3716 http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.3716.html

Trembley JH, Kren BT, Abedin MJ, Vogel RI, Cannon CM, Unger, GM, Ahmed K: CK2 Molecular Targeting —Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer. Pharmaceuticals 2017, 10, 25; doi:10.3390/ph10010025

Research coordinator search starts over

Last issue we announced that Nick Blank would start as the new research coordinator in the Division of Anatomic Pathology on April 3.  Unfortunately, Blank was involved in a serious boating accident and is unable to honor his commitment.  A new recruitment effort has started.

Reminder:  Next research forum is Thursday, April 13 at 5:00 pm in the Dale Shephard Room, Campus Club featuring Ameeta Kelekar “Metabolic reprogramming in cancer therapy and immunotherapy”

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, April 10, 2017

LMP News, March 27, 2017

Register now for April 1 Flow Cytometry conference

It’s not too late to register for the Twin Cities regional flow cytometry conference on Saturday, April 1 from 9:30am – 1:45 pm. in 450 MCRB.  The conference features presenters from the U of M, Mayo, Allina, and FlowJo.  Registration is free and lunch will be provided.  RSVP to Amy Olson: olson017 at umn.edu.  RSVP needed by 3/29/16 for appropriate lunch count. Program details are linked on the front page of our web page https://www.pathology.umn.edu/

LMP searches are successful

Two new assistant professors will start this year in our department in addition to Joe Rudolf who we presented in December.  Rob Bell begins in early June in neuropathology and in the Institute of Translational Neurosciences (ITN) as an ITN scholar.  Bell will also have a joint appointment in the Department of Ophthalmology and Visual Neurosciences.  He received his MD at University College Cork, did his residency at Rutgers and completed two fellowships (ophthalmic and neuropathology) at Johns Hopkins.  Pawel Mroz starts July 10 in the Division of Clinical Pathology in both molecular genomics and hematopathology.   Mroz will also be a member of our Division of Molecular Pathology and Genomics (MPG).  He is completing his molecular genetic pathology at the University of Michigan.  Previously he graduated from medical school at the Medical University of Warsaw, completed an AP/CP residency at Northwestern University and a hematopathology fellowship at Michigan.  

Research coordinator starts in AP

Nick Blank starts as the new research coordinator in the Division of Anatomic Pathology on April 3.  Blank was previously a clinical research coordinator at the Mayo Clinic.  He received his BS in chemistry from Winona State University and a masters in health care management at Globe University.  Blank’s email is blan0268@umn.edu and phone is 612-626-7645.

Hoffman gives talk

Bill Hoffman was on the lecture trail again this March and gave a talk as part of the University of Minnesota Rochester Connects program.  The title of his talk was “Stem Cell Research: A Look Back and a Glimpse Forward”.   The evening highlight was meeting with a group of Shattuck St. Mary’s students who attended the talk. (see photo below).

We welcome our new PGY-1  Residents

The Match was finalized on Friday and we will have four new AP/CP residents starting in July:  Cade Arries (University of Minnesota), Pooria Khoshnoodi (Tehran University), Aimi Toyama (University of Kentucky), and Hira Yousaf (Allama Iqbal Medical College in Pakistan).    

Ordering computers confuses everyone

We used to be able to buy computers directly from the bookstore and place on our AHC contract. However as of March 16 the AHC-IS (in their newsletter at https://goo.gl/55WNMb) announced that devices purchased outside of the AHC-IS process will not be added to AHC support.  Apparently bookstore computers are consumer grade rather than business grade and AHC computers are required to be able to be patched, encrypted, etc. which you can’t do with consumer grade.  Who knew?  We didn’t.  This policy could be changed in the future.  As a reminder, the AHC-IS said that devices not supported by them should not be used on the University network and should never be used to handle private or restricted data.  

Faculty publish

Boylan, K.L.M., Buchanan, P.C., Manion, R. D., Shukla, D.M., Braumberger, K., Bruggemeyer, C., and Skubitz, A.P.N.  (2017)  The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferation.  Oncotarget 8(6):9717-9738.

RSVP for LMP’s annual resident and fellow graduation dinner

It’s not too early to send in your reservation for this annual event to recognize our trainees.  The dinner will be held at the Campus Club on Wednesday, Ma

Reminder:  Next research forum is Thursday, April 13 at 5:00 pm in the Dale Shephard Room, Campus Club featuring Ameeta Kelekar “Metabolic reprogramming in cancer therapy and immunotherapy”

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Shattuck St. Mary's

Publication date: 
Monday, March 27, 2017

LMP News, March 13, 2017

Dean updates LMP faculty

Dean Jackson met with faculty on March 8.  He reviewed the high points of the legislative session which includes funding requests to expand clinical cancer trials throughout the State of Minnesota and build a new health sciences education building.  Faculty might be interested in the future research “hub” that will be built across from Freshii in PWB.  The “hub” will house staff to help you with all research including clinical trials.  Available will be staff from the IRB, tech transfer, SPA, biostatisticians, bioinformaticians, and Fairview.  MHealth is in its renewal year so we will see activity on this before June.  Research ranking is still falling but LMP ranks 3rd among the clinical departments in research funding.  The Dean also encouraged us to participate in the Chainbreaker bicycle rides to fund cancer research August 11-13.  Here’s the link:  https://www.med.umn.edu/news-events/chainbreaker-ride

Programs receive accreditation

The Clinical Chemistry fellowship program was recently reaccredited through the end of 2021 by ComACC.  Danni Li is the program director.  The American College of Medical Genetics and Genomics combined the now separate molecular and cytogenetic training options into one single cytogenetics and genomics three-year fellowship.  Betsy Hirsch and Michelle Dolan submitted the outline of a new integrated program at the University of Minnesota which was approved by the ACMGG for five years.

USCAP meeting draws abstracts

LMP was well represented in abstracts at this year’s annual meeting of USCAP in San Antonio last week.   Chief Resident Maryam Shahi had the most with (5) followed by Aqsa Nasir, resident, (3) and one each for Victor Santiago, resident, Regina Plummer, resident, Ioana Moisini, cytopath fellow, and Hannah Christensen, post sophomore fellow.  See photo attached.  Two medical students also presented AP related posters including Matt Root and Amy Fang. The department sponsored a reception which attracted several alum and former faculty including Raouf Nakhleh, Mayo, Laura Moench, Fairview Southdale, Mohamed El Hag, Pittsburgh, Hannah Krigman, Wash U. and Stefan Pambuccian (Loyola).  Amy Olson assisted with the reception. 

Li gives invited talk

Danni Li gave a talk last month on “When lab results did not make sense: clinical chemistry case series” for the Citywide Endocrine conference.

Resident receives grant

Aqsa Nasir received a $2500 grant from the department for her project “Clinical significance of low grade follicular lymphoma with high proliferative index.”  Nasir will collaborate with Livia Hegerova, Veronika Bachanova and Sophia Yohe on the project. 

EM Laboratory will hold open house

The EM Laboratory open house (C213 Mayo) is this Wednesday, March 15 from 1-3 p.m.  See our short feature about the facility on our website.

Faculty publish

Hanse, E. A., C. Ruan, M. Kachman, D. Wang, X. H. Lowman, and A. Kelekar. Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer. Oncogene advance online publication http://www.nature.com/doifinder/10.1038/onc.2017.36

Administrative offices close on March 17

The University is on spring break this week and Friday, March 17, is an official University holiday.  Administrative offices will be closed.  Some will consider this an opportunity to celebrate St. Patrick’s Day. 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

USCAP

 Mahmoud Khalifa and Maryam Shahi at USCAP meeting

Publication date: 
Monday, March 13, 2017

LMP News, February 27, 2017

Jameson receives Minnesota Partnership grant

Stephen Jameson is the lead principal investigator of a research award of $996,803 through the Minnesota Partnership for Biotechnology and Medical Genomics.  The grant titled “Testing susceptibility of ‘dirty’ mice to induction of asthmatic disease and lung pathology” establishes a new collaboration with Hirohito Kita at Mayo Clinic.

Orr receives Ataxia Foundation award

Harry Orr was awarded a $100,000 pioneer SCA translational grant from the National Ataxia Foundation.  The funding is for his project “Toward an ASO therapy for Spinocerebellar Ataxia Type I”.

McKenna gives talk

David McKenna was invited by the FDA CBER (Center for Biologics Evaluation and Research) to talk on "Recipients of Hematopoietic Progenitor Cells" at the FDA Public Workshop entitled, "Identification and Characterization of the Infectious Disease Risks of Human Cells, Tissues, and Cellular and Tissue-based Products.” McKenna also was a member of the panel at the meeting on February 9in College Park, MD.

EM Laboratory will hold open house

The EM Laboratory is scheduled to open early next month.  Stop in at the open house on Wednesday, March 15 from 1-3 p.m.  We will also have a short feature about the facility on our website to coincide with its opening.

Faculty publish

Serotype Distribution, Population Structure, and Antimicrobial Resistance of Group B Streptococcus Strains Recovered from Colonized Pregnant Women. Teatero S, Ferrieri P, Martin I, Demczuk W, McGeer A, Fittipaldi N.J Clin Microbiol. 2017 Feb;55(2):412-422. doi: 10.1128/JCM.01615-16.PMID: 27852675

Serotype IV Sequence Type 468 Group B Streptococcus Neonatal Invasive Disease, Minnesota, USA.Teatero S, Ferrieri P, Fittipaldi N.Emerg Infect Dis. 2016 Nov;22(11):1937-1940. doi: 10.3201/eid2211.152031.PMID: 27767922 Free PMC Article

We have slides from Academic Track meeting

Dean Steer forwarded his slides from the meeting last week on the Academic Track.  We have posted on our google site https://sites.google.com/a/umn.edu/lmp/   Just click on Faculty Meetings.

Everything is due February 28

  1. Employee PAT reviews need to be completed by February 28 if you are a supervisor.
  2. Faculty annual reviews are due to Jean Kurata.  This is an absolute deadline.
  3. REPA (Report of External Professional Activity) forms are due.

Meetings are in your future

March 6 at 8-10 pm LMP reception at USCAP mtg in Conference Room 17, Marriott River Center Hotel

March 8 at 9:00 am in 450 MCRB.  Dean Jackson is coming for his annual check-in.

March 9 at 5:00 pm in Dale Shephard Room.  Research Forum with Bharat Thyagarajan on the Division of Molecular Pathology and Genomics.

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, February 27, 2017

LMP News, February 13, 2017

Where’s Waldo

Three faculty and/or trainees are featured on the current cover of Clinical Chemistry.  The cover features faces of Young Clinical Laboratorians (SYCL) members who have participated in the building of the Clinical Chemistry Trainee Council.   See if you can find our three on the cover.   Here are a few hints:  one is in a fellowship, one frequently rides a bike to work, and the last is based at an off-campus site.  (answers at the bottom).

http://clinchem.aaccjnls.org/content/63/2.cover-expansion

Reception planned for Minnesota alumni and friends at USCAP meeting 

Join Drs. Robert McKenna and Mahmoud Khalifa for a reception sponsored by the Department of Laboratory Medicine and Pathology and held in conjunction with the USCAP annual meeting in San Antonio, Texas. 

Marriott Rivercenter Hotel 
San Antonio, Texas
Conference Room 17
Monday, March 6, 2017
8 - 10 p.m. 

 

PAT reviews due February 28

LMP employees did a great job completing their self-assessments (100%) for their job performance in 2016.  If you are a supervisor, your reviews are due Tuesday, February 28.  You should also hold your meeting with your employee to discuss the review.  Need help?  Call or e-mail Hannah Bergquist at 624-7115 or bergq064@umn.edu

Faculty annual reviews are also due February 28

Annual review forms were e-mailed to all faculty on January 31 to cover your progress in 2016.   Forms are also available for download from our Google site https://sites.google.com/a/umn.edu/lmp/annual-faculty-review-process

Faculty will vote on new academic track

The Medical School will review input it received on the new Academic Track proposal and send out to all faculty for a vote in mid-February.  Faculty will have approximately two weeks to vote on the adoption of this new track which will replace clinical scholar track, research track and the teaching track.  LMP will have a faculty meeting on February 22 with Dean Cliff Steer to discuss the proposal.  We ask that you hold your vote until after that meeting.  The original proposal is posted on our google site at https://sites.google.com/a/umn.edu/lmp/

Faculty meetings are on your schedule

February 22 at 9:00 am in 450 MCRB.  Cliff Steer:  the new Academic Track proposal.  

March 8 at 9:00 am in 450 MCRB.  Dean Jackson is coming for his annual check-in.

Research Forum with Bharat Thyagarajan on the Division of Molecular Pathology and Genomics March 9 at 5:00 pm in Dale Shephard Room. .

Faculty publish

Specificity of B-Type Natriuretic Peptide Assays: Cross-Reactivity with Different BNP, NT-proBNP, and proBNP Peptides Amy K. Saenger, Olaia Rodriguez-Fraga, Ranka Ler, Jordi Ordonez-Llanos, Allan S. Jaffe, Jens Peter Goetze, Fred S. Apple Clinical Chemistry, vol. 63 no. 1 351-358 DOI: 10.1373/clinchem.2016.263749  http://clinchem.aaccjnls.org/content/63/1/351

Best Practices for Monitoring Cardiac Troponin in Detecting Myocardial Injury Fred S. Apple, Allan S. Jaffe, Scott Sharkey, Peter Kavsak, Michael C. Kontos, AmyK. Saenger, Stephen Smith Clinical Chemistry, vol. 63 no. 1, 37-44 DOI: 10.1373/clinchem.2016.257428 http://clinchem.aaccjnls.org/content/63/1/37

 

Answers:  Sarah Drawz, Mike Linden, Amy Saenger

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

Publication date: 
Monday, February 13, 2017

LMP News, January 30, 2017

LMP strategic plan committees continue to meet

The Division of Molecular Pathology and Genomics has a webpage http://www.pathology.umn.edu/molecular-pathology-and-genomics   and is planning its first full faculty meeting on February 28.  The Translational Research Committee is working with the TWG groups in the Cancer Center to increase interactions between these groups and our pathologists.  The committee is also planning on using the Research Forums in a more directed way.  Stay tuned for details.

EM facility to open

The electron microscope is installed and the new EM facility in C213 is expected to open at the end of February.  Prior to this, all EM work was outsourced to Hennepin County Medical Center which created many inefficiencies to our workflow and turnaround time.   The facility will bring our renal division on par with other academic medical centers.

New grandchild for the Khalifa family

Just over a week ago, Aya A. Khalifa, became the newest member of the Khalifa family.  See her photo attached at the end of this newsletter.  Everyone is happy (especially Grandfather) and doing well. 

Killeen takes on new role

Effective January 1, Tony Killeen was named as Secretary of the American Association for Clinical Chemistry (AACC).  This is a three year term (2017-2019).  The AACC is a global scientific and medical professional organization dedicated to clinical laboratory science and its application to healthcare.    

Watch for IRS Form 1095-C

The University will send you a Form 1095-C that says you had health coverage through the U in 2016.  You will need the health insurance information on the form to complete your 2016 federal income tax return but you do not need to attach the form to your return.

Faculty meetings are on your schedule

February 8 at 9:00 am in 450 MCRB.  Jakub Tolar is a guest speaker in his role as executive vice dean and the Epic upgrade team will give a brief update

February 22 at 9:00 am in 450 MCRB.  Cliff Steer in his role as associate dean for faculty affairs will discuss the new Academic Track proposal.  This proposal is available on our google site at https://sites.google.com/a/umn.edu/lmp/  We hope to have time to review our new rating system for faculty reviews at this meeting also.

March 8 at 9:00 am in 450 MCRB.  Dean Jackson is coming for his annual check-in.

Faculty publish

Amy Karger has published an article that questions the utility of delta checks, a longstanding quality control process used by clinical labs to detect lab errors:  Karger AB. To delta check or not to delta check? That is the question...J Appl Lab Med Jan 2017, 1 (4) 457-459; DOI: 10.1373/jalm.2016.022020.

Additionally, a podcast interview with Karger related to this article on delta checks can be found on the Journal of Applied Laboratory Medicine website:  https://www.aacc.org/publications/the-journal-of-applied-laboratory-medicine/jalm-talk

A second article addresses the debate surrounding universal lipid screening in children:  Karger AB, Saenger AK. A Setback to Universal Pediatric Lipid Screening and a Call for More Research. Clin Chem Feb 2017, 63 (2) 620-621; DOI: 10.1373/clinchem.2016.267989.

Free biostatistics consulting available

The Division of Biostatistics is offering statistical consulting free of charge in conjunction with the biostatistical consulting course for their graduate students during spring semester 2017.  The hour long meetings include support for study design, sample size, power calculations, statistical analysis and interpretation, and statistical sections of grants or manuscripts.  Learn more here: https://sites.google.com/a/umn.edu/pubh7465a/for-investigators

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Aya

Publication date: 
Monday, January 30, 2017

LMP News, January 17, 2017

Linden on search committee

Mike Linden will be on the search committee for the Director of Hematology, Oncology and Transplantation (HOT) division in the Department of Medicine.  Dan Weisdorf announced recently that he will step down from that position.

How we are filling Sally Palm’s position

Is there life after Sally Palm’s retirement?  We hope so.  As of January 3 Nicole Hilmoe took over responsibility for LMP facilities.  Hilmoe will do the annual space surveys and keep our space inventory up-to-date.  She will also help with space requests.  Safety officer is Deb Lins, research manager in the Center for Immunology.  Computer issues call 1-HELP or email help@umn.edu.  Be prepared to provide your name, telephone number, device number of your computer and a description of your problem.  

Funches hired as new Outreach Sales Manager

Laura Funches started her new position as sales manager for the UMP Outreach Laboratories last week.  Funches most recently worked as an analyst with the Fairview Health Services Laboratory Information Support team.  She also has outreach experience at University of Colorado Health where she worked with internal and external clients on referral testing.  Janet Fennert is officially retired but will work through January orienting Funches to her new position. 

Resident gets recognized for abstract

Shelly Williams's abstract was selected as a top 3 poster at the recent AABB annual meeting in Orlando.  Her abstract was titled “CD3/CD19 Depleted Natural Killer Cell Production under Good Manufacturing Practices. “ 

Hoffman speaks on stem cells

Bill Hoffman recently spoke on stem cells at the Men’s Club of the Highland Park Jewish Community Center.  Hoffman is a co-author with Leo Furcht on the book, “The Stem Cell Dilemma”.

Orr receives funding

Harry Orr received an award from the Winston and Maxine Wallin Neuroscience Discovery Fund for his proposal on “Development of an ASO-based Therapy for Spinocerebellar Ataxia Type 1.”  The award is $75,000.  

Faculty publish papers

Boylan, K.L.M., Buchanan, P.C., Manion, R.D., Shukla, D.M., Braumberger, K., Bruggemeyer, C., and Skubitz, A.P.N.  “The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate” Oncotarget (2016).

Danni Li, Robin Thomas, Michael Tsai, David Vock, Susan Greimel and Fang Yu.  “Vascular biomarkers to predict response to exercise in Alzheimer’s disease: the study protocol” In BMJ Open: https://goo.gl/2sJnb2

Reminder to update to residency goals & objectives and didactics

Faculty rotation directors need to update the goals and objectives for resident rotations at UMMC.  Rotation directors are also encouraged to increase their didactic teaching, perhaps looking at new teaching methods including short YouTube talks or study sets for esoteric information.  Deadlines are listed below.  Send updates to Maggie McGough at truax031@umn.edu

First draft goals and objectives                  February 6, 2017

Final draft goals and objectives                  March 6, 2017

Updated evaluations                                   March 6, 2017

Didactic lectures                                         April 3, 2017

Dates to remember

  • First faculty meeting of 2017 is scheduled for Wednesday, February 8 at 9:00 am in 450 MCRB.  Jakub Tolar is a guest speaker in his role as executive vice dean. 

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Tuesday, January 17, 2017

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