News

LMP News, January 16, 2018

Faculty receive MCC Awards

Kaylee Schwertfeger and Mike Farrar received funding for their applications to the Masonic Cancer Center Pre-RO1 Pilot grant program.   Schwertfeger received $100,000 for one year for her proposal “Regulation of macrophage function by STAT3 and STAT5 during breast cancer growth and progression.”  Farrar also received $100,000 for one year for his proposal “Sos1 as a novel oncogene in acute lymphoblastic leukemia.”  Awardees are required to apply for federal funding (RO1 or comparable) within one year of the award. 

Karger reaches high altmetric scoring for 2017 Ebola article

The journal, Lab Medicine, recently announced that the article “Establishing a stand-alone laboratory dedicated to the care of patients with Ebola Virus Disease” received the second highest altmetric score (15) of all papers in the journal in 2017.  Karger was senior author on the paper.  The altmetric score is one of the ways the Oxford University Press calculates the reach of a published article.  If you missed it earlier, here is the link to the article:  https://academic.oup.com/labmed/article/48/2/188/3068837

Nelson gives seminar

Andy Nelson spoke at the Precision Medicine Seminar, College of Pharmacy, on January 5.  His talk was “There and Back Again:  A Molecular Pathologist’s Perspective on Developing NGS-based Clinical Oncology Diagnostics.”  

Pathologists’ Assistants take on national roles in AAPA

Both Nea Moyer and Meghan Pickard assumed roles in the American Association of Pathologists’ Assistants (AAPA) recently.  Moyer is the National Content Management Chair which in involved in PACE compliance, peer review of articles, quizzes, scholarships/travel grants, content management and organizing staff writers.  Pickard is the Vice Chair of Education.  She will oversee/organize AAPA conferences, organize topics in the AAPA journal, and will peer review publications and study materials for students.

Faculty Publish

We’d like to highlight Debbie Powell’s new publication that focuses on an innovative way to look at medical education. 

Powell DE and Carraccio C. Becoming a Physician: Toward Competency-Based Medical Education. N Engl J Med 2018, 378:5-7 http://www.nejm.org/doi/full/10.1056/NEJMp1712900?query=TOC

Flanagan ME, Larson EB, Walker RL, Keene CD, Postupna N, Cholerton B, Sonnen J, Dublin S, Crane PK, Montine TJ.  Associations between use of specific analgesics and concentrations of amyloid-β 42 or phosphor-tau in regions of human cerebral cortex. Journal of Alzheimer’s Disease. Vol. 61, no.2, pp 653-662, 2018. https://www.ncbi.nlm.nih.gov/pubmed/29226863

100% Completion reached on UMP course

Thanks to the entire physician faculty who completed the UMP’s 2017 Annual Required Compliance & Risk Management E-Learning Course.  We reached100% participation by the deadlineand will be eligible for a rebate on our medical liability insurance.  A shout out goes to Jean Kurata for diligently reminding faculty to complete the training. 

Prepare for Super Bowl Week

The Super Bowl is scheduled for Sunday, February 4 but the week before and the Monday after will bring events and people into the Twin Cities and on campus.  Check this site for current updates:  https://twin-cities.umn.edu/super-bowl  Here are a few things to remember:

Light Rail

There is no light rail service on Sunday, February 4 except for Super Bowl ticket holders.  Buses will be available to every day commuters.  You will be able to use the green line from Stadium Village to Union Depot in St. Paul on game day.

The US Bank Stadium light-rail stop will be closed for two days prior to the Super Bowl including rush hour on Friday, February 2.

U Parking Contracts

Northrup parking will be closed January 15 – February 13

Gateway Lot – relocated to Maroon Lot from January 26 – February 7

Game day (Sunday, February 4) Washington Avenue Ramp, Fourth St. Ramp, Oak Street Ramp, University Avenue Ramp parking contracts are all relocated to the East River Ramp.  If you park at the other ramps it will cost you an event fee of $40.00.

Miscellaneous

There are 37 NFL events planned on campus during the week prior to the game.  There will be additional traffic, road and sidewalk closures, venue construction, building restrictions and increased security.

10,000 Super Bowl volunteers will be stationed out of the U of M Field house, located behind Civil Engineering, north of Washington Avenue.

One of the teams will practice on campus, likely in the indoor football practice facility located on 15th Avenue SE (North of Dinkytown).

Upcoming events of interest or things to do

First quarter 2018 Part A Time reporting is January 22-February 4 (due February 8)

  •  2017 Performance appraisal process for civil service, bargaining unit and P&A employees started last month.  Self-evaluations began December 19 and are due by January 23.  Supervisor evaluations are due by February 28. 
  • Medical School/UMP Faculty and Staff Forums are scheduled for Wednesday, January 17 at 5:30 pm in 2-470 PWB or Thursday, January 18 at 7:00 am in 2-650 Moos Tower.  The Dean and Mac Baird will discuss plans to improve performance and grow the UMPhysicians practice. 

  

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Tuesday, January 16, 2018

LMP News, December 18, 2017

LMP study generates national coverage

Danni Li’s study on biotin (JAMA 2017:318 (12) 1150-1160) has earned national coverage due to the FDA issued safety warning that biotin or “super vitamin” in dietary supplements can interfere with common lab tests.  News coverage appeared in Consumer Reports, WebMD, CAP Today, and Star Tribune among others.  Study co-authors include Amy Karger and Tony Killeen.  See Trib link: http://www.startribune.com/super-vitamin-proves-disruptive-to-medical-tests/462628153/ 

Linden gives interview

Mike Linden was interviewed for the American Society of Hematology (ASH) News Daily (the daily newspaper at the annual ASH meeting) last week about his involvement in building hematology capacity in Arequipa, Peru. http://www.nxtbook.com/nxtbooks/customnews/ashnewsdaily2017_Monday/index.php#/32

Steffes receives another contract award

Mike Steffes is not slowed down by his phased retirement.  He has received a $1.9 million award from NIH via George Washington University for the GRADE study, “Glycemia reduction approaches in diabetes:  a comparative effectiveness study.”  The testing will be done at ARDL. 

Karger receives Grant-in-Aid

Amy Karger was awarded a U of M Grant-in-Aid for $31,542 for an ancillary study to the PERL clinical trial, “Analysis of the discrepancy between estimated and measured GFR in the PERL cohort.” The funding runs from January 1, 2018 through June 30, 2019.

Yohe and Linden visit CAP headquarters

Sophia Yohe and Mike Linden were visitors at the College of American Pathologists (CAP) headquarters in Northfield, Illinois recently to attend the CAP Committee Chairs Orientation.  Starting this January Yohe will chair the Personalized Healthcare Committee (Molecular Pathology and Genomics Cluster) and Linden will chair the Diagnostic Immunology Resource Committee (Hematology Cluster).

2018 Part A Time reporting dates announced

These are the weeks clinical faculty will be asked to do Part A time reporting in the New Year.  Note them on your calendar.  

January 22-February 4 (due February 8)

April 23 – May 6 (due May 10)

July 23 – August 5 (due August 9)

October 22 – November 4 (due November 8)

Administrative Office closed and LMP News on brief hiatus

The University of Minnesota will be closed on December 25, 26 and January 1.  LMP News will be on hiatus until January but please continue to send in news items to kenny001@umn.edu.

Upcoming events of interest or things to do

Physicians need to complete the UMP’s 2017 Annual Required Compliance & Risk Management E-Learning Course by December 31, 2017.  You need to access this through your Workday account.  If you are having issues with Workday contact Hannah Bergquist at 624-7115 or bergq064@umn.edu 

Deadline for the spring funding cycle of Graduate School grant-in-aid applications is January 2, 2018.  https://research.umn.edu/funding-awards/grant-aid

Resident Research Grant deadline is January 15, 2018.  More information on the process is at https://www.pathology.umn.edu/residency-fellowships/residency/research-experience

 2017 Performance appraisal process for civil service, bargaining unit and P&A employees start this month. 

Self-evaluations begin December 19 and are due by January 23.  Supervisor evaluations are due by February 28.

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, December 18, 2017

LMP News, December 4, 2017

Steffes receives new contract

The NIH awarded new funding of $649,666 (first year) to PI Mike Steffes as part of the Epidemiology of Diabetes Intervention and Complications grant (EDIC).    Amy Karger and Amy Saenger are co-investigators on the grant which will be performed at ARDL.  The grant is expected to run through April 30, 2022.

Karger elected to national office

Effective January 1, 2018 Amy Karger will begin a 6-year term on the Board of Directors for the American Board of Clinical Chemistry. As a board member, she will help oversee the certification of laboratory directors for high complexity testing in clinical laboratories, and will serve on the clinical chemistry board examination sub-committee. 

Ahmed’s work featured on AJVR cover

An image from the manuscript, “Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats” published in the American Journal of Veterinary Research (AJVR) on August 2017, Vol 78, No. 8, 946-953) was used as the cover image for the current issue of AJVR, http://avmajournals.avma.org/toc/ajvr/78/11). Khalil Ahmed is last author on the manuscript.

Saenger is invited speaker and panelist

Amy Saenger was an invited speaker at the American Heart Association Scientific Sessions in Anaheim, CA recently.  Her presentation was on “Laboratory challenges to implementing high-sensitivity troponin assays.”  She was also an invited expert panelist at the FDA open meeting and workshop on Cardiac Troponin.  She spoke on behalf of the CAP regarding current lab utilization of cardiac troponin assays. 

More opportunities to apply for bridge funding

The Medical School/University of Minnesota Foundation Bridge Grant Program provides support for competitive applications from faculty who have not been successful in competitively renewing an NIH grant. The current program makes one time awards of up to $75,000 and has been in force since 2011. The following link describes the program: https://goo.gl/bnB8FW. Since competitive renewal applications can be reviewed at least three times per year by NIH, the Medical School expanded the application deadlines to: March 15, June 15, September 15 and December 15. Note the next deadline is December 15, 2017.

Faculty publish

Eber AE, Rosen A, Oberlin KE, Giubellino A, Romanelli P. Ichthyosiform Pityriasis Rubra Pilaris-Like Eruption Secondary to Ponatinib Therapy: Case Report and Literature Review  Drug Saf Case Rep. 2017 Nov 14;4(1):19. doi: 10.1007/s40800-017-0055-y. PMID: 29138996 https://www.ncbi.nlm.nih.gov/pubmed/29138996

Gunsolus IL, Jaffe AS, Sexter A, Schulz K, Ler R, Lindgren B, Saenger AK, Love SA, Apple FS. Clin Biochem. 2017 Dec;50(18):1073-1077. Sex-specific 99th percentiles derived from the AACC Universal Sample Bank for the Roche Gen 5 cTnT assay: Comorbidities and statistical methods influence derivation of reference limits.  doi: 10.1016/j.clinbiochem.2017.09.009. 

ARDL reports high customer satisfaction

LMP’s Advanced Research and Diagnostics Laboratory (ARDL) performs over 308,000 test results on 41 different studies or projects.  The recent customer satisfaction survey (105 responses from 20 studies) shows that 78% of clients strongly recommend our laboratory services and 89% of clients are extremely satisfied with their overall experience

Employee Recognition event is this Wednesday

Once a year we gather together to recognize our LMP faculty, staff and students and our UMMC laboratory staff.  The event is scheduled in The Commons Hotel (right across the street) in the ball room from 3 pm to 7 pm.  There will be food and just for fun team building casino games.  Spread the word!  

Upcoming events of interest or things to do

LMP Faculty meeting is scheduled for Wednesday, December 6 at 9:00 am (right after Grand Rounds) in 450 MCCB.   Agenda:  MD/PhD program, new rating system for annual faculty reviews and Dos and Don’ts for interviews.  All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop Path to Publication on how to write for peer-reviewed journals.  This fall’s workshop takes place on December 11 from 12:30 – 4:30 pm in the McNamara Alumni Center (right across Washington Avenue).  Here is the link to register: https://goo.gl/ktg6Ns  

Research Forum is scheduled for Thursday, December 14 from 5-7 in the Dale Shephard room at the Campus Club.  Featured are Innovations Initiative proposals from Joe Rudolf and Tony Killeen and Alessio Giubellino with Paari Murugan, Mahmoud Khalifa and Faqian Li   RSVP with Jean, jkurata@umn.edu

Physicians need to complete the UMP’s 2017 Annual Required Compliance & Risk Management E-Learning Course by December 31, 2017.  You need to access this through your Workday account.  If you are having issues with Workday contact Hannah Bergquist at 624-7115 or bergq064@umn.edu

Deadline for the spring funding cycle of Graduate School grant-in-aid applications is January 2, 2018.  https://research.umn.edu/funding-awards/grant-aid

Resident Research Grant deadline is January 15, 2018.  More information on the process is at https://www.pathology.umn.edu/residency-fellowships/residency/research-experience 

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, December 4, 2017

LMP News, November 20, 2017

MPG co-sponsors GenoFest

Earlier this month our division of Molecular Pathology and Genomics co-sponsored the annual GenoFest with the U of M’s Genomics Center (UMGC).  Genofest brings together staff and faculty across the University with the tech companies that provide UMGC with its advanced genomic capabilities.   LMP had a number of speakers at the event and three won a random lottery for a $2,000 grant:  Andy Nelson, Pawel Mroz and Aruna Rangan, our molecular genetic pathology fellow. 

Ferrieri travels North

Pat Ferrieri gave an invited talk to the National Molecular Microbiology Diagnostic Users Group’s annual meeting in Toronto this month.  Her topic was “Molecular Detection of Group A Streptococcus from Pharyngeal ESwabs™.”

It’s #3 in the Andy Johnson Family

Althea Marion Johnson was born November 6 to the Johnson Family making a perfect trio of little girls.  Mom, Althea and reportedly Dad are doing well.  See photo below.

U of M Secure Wi-Fi is retiring

If you are used to logging into the U of M Secure site for your Wi-Fi on campus, please start using Eduroam (same login).  U of M Secure will be retired at the end of December.  If you are having any issues connecting to Wi-Fi let us know and we can pass on your issues to OIT (Office of Information Technology).  For more information:  https://it.umn.edu/technology/eduroam 

Graduate program faculty added to LMP website

Part of our strategic plan is to attract MD/PhD students into our residency program.  One of our small steps to market ourselves is to add a list of faculty who currently hold faculty appointments in various graduate programs.  The list drops down from the Research tab and can be found at https://www.pathology.umn.edu/research/graduate-program-faculty  Let us know of any omissions.

Celebrate our people on December 6

Once a year we gather together to recognize our LMP faculty,staff and students and our UMMC Laboratories staff.  The event is schedule in The Commons Hotel(right across the street) in the ball room from 3 pm to 7 pm.  There will be food and just for fun team building casino games.  Spread the word! 

Residents can apply for funding

Residents can apply for research funding of up to $2500; due date forproposals is January 15, 2018.  Proposals will be reviewed by a faculty committee.

More information on the process is at: https://www.pathology.umn.edu/residency-fellowships/residency/research-experience

Faculty publish

Vahidi S, Stewart J, Amin K, Racila E, Li F.  Metastatic medullary thyroid carcinoma or calcitonin-secreting carcinoid tumor of lung? A diagnostic dilemma in a patient with lung mass and thyroid nodule.  Diagnostic Cytopathology. 10 Nov 2017, DOI: 10.1002/dc 23852  http://onlinelibrary.wiley.com/doi/10.1002/dc.23852/full  (Note: Dr. Vahidi is a surg path fellow.)

Amy Skubitz is the senior author of a chapter in the latest edition of the book "Principles and Practice of Clinical Research" (4th Edition) entitled, "Management of Patient Samples". Editors: J Gallin, F Ognibene, and L JohnsonHardcover ISBN: 9780128499054, eBook ISBN: 9780128499047, Imprint: Academic Press,Published Date: 17th November 2017.

Upcoming events of interest

  • Open Enrollment for health care benefits at the U of M runs through November 30.  If you are happy with your benefit selection you don’t need to take any action.  If you want a flexible spending account for 2018 or if you want to change your insurance carrier you will need to enroll for 2018.  Go to MyU/My Benefits to make your selections. 
  • The P3 grant writing program for assistant professors is still open for applications until Monday, December 4. For more information:  https://hub.med.umn.edu/faculty-affairs/faculty-development-advancement-opportunities/grant-writing
  • LMP Faculty meeting is scheduled for Wednesday, December 6 at 9:00 am (right after Grand Rounds) in 450 MCCB. 
  • All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop Path to Publication on how to write for peer-reviewed journals.  This fall’s workshop takes place on December 11 from 12:30 – 4:30 pm in the McNamara Alumni Center (right across Washington Avenue).  Here is the link to register: https://goo.gl/ktg6Ns 
  • December Research Forum is scheduled for Thursday, December 14 from 5-7 in the Dale Shephard room at the Campus Club.  Featured are Innovations Initiative proposals from Joe Rudolf and Tony Killeen and Alessio Giubellino with Paari Murugan, Mahmoud Khalifa and Faqian Li
  • Physicians need to complete the UMP’s 2017 Annual Required Compliance & Risk Management E-Learning Course by December 31, 2017.  You need to access this through your Workday account.  If you are having issues with Workday contact Hannah Bergquist at 624-7115 or bergq064@umn.edu

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Andrew Johnson baby

Publication date: 
Monday, November 20, 2017

LMP News, November 6, 2017

McKenna receives President’s Award

Dave McKenna recently received a 2017 President’s Award at the annual  American Association of Blood Banks (AABB) meeting in San Diego.  This award recognizes McKenna and others for their leadership and perseverance in developing cellular therapy expertise in the AABB. “Their tremendous devotion to the association and visionary approach has brought cellular therapies to AABB members and has brought cellular therapy members to AABB,” read the citation.

Faculty busy taking board examinations

Congratulations to three of our new faculty members who recently received notification that they passed their specialty board certification examinations.  Alessio Giubellino received his dermatopathology certification; Maggie Flanagan passed the neuropathology portion of the combined anatomic pathology and neuropathology certification examination, and Pawel Mroz was successful in the molecular genetic pathology examination. 

Cohn travels to Japan

Claudia Cohn was a guest speaker to the Japanese Red Cross Society in Fukuoka, Japan last week.  Her presentation was on platelets stored in additive solutions.

Movember Award goes to Dehm

Scott Dehm was awarded a two year Movember Foundation-Prostate Cancer Foundation Challenge award for his project “Therapeutic targeting of AR variant prostate cancer with a novel antibody drug conjugate.”  The first year award is $161,837.  Paari Murugan is a co-I on the grant. 

Schwertfeger speaks at 1st annual Midwest Metastatic Breast Cancer Conference

Kaylee Schwertfeger was a featured speaker last weekend at the first Midwest conference designed for both metastatic breast cancer patients and the health care professionals who care for them.  Her talk was on “Basic science and how do cells spread?” 

Follow up to the October 25 faculty meeting

Brochures on the vision benefit and Roth 401k can be downloaded from our faculty google site at https://sites.google.com/a/umn.edu/lmp/faculty-meetings  If you want to discuss benefits with Val Bock; her contact information is vbock10@umphysicians.umn.edu or 612-884-0788.  You need to sign into workday to access the Vision benefits enrollment.  You have until November 8 to enroll.  If you do not know your Workday login information, please contact UMP's IT Service Desk at 612.884.0888, option 0. State that you need your Workday username and that your password needs to be reset. The Workday link is:  https://www.myworkday.com/umphysicians/login.flex

Funding Opportunities added to LMP website

We’ve collected information on various small grant opportunities available at the University on one webpage with links to application sites.  Deadlines for these grants vary.  Let us know if you know of any funding sources we have overlooked.  https://www.pathology.umn.edu/research/funding-opportunities

Open enrollment runs November 1-30

The good news is medical and dental plan rates haven’t changed for 2018.  If you are happy with your benefit selection you don’t need to take any action.  If you want a flexible spending account for 2018 or if you want to change your insurance carrier you will need to enroll for 2018.  Go to MyU/My Benefits to make your selections.  

P3 program is open for registration

If you are an assistant professor interested in help with your first K or R series grant consider applying for the Assistant Professors: NIH Proposal Preparation program which will be held this winter.  Application deadline is Monday, December 4. For more information:  https://hub.med.umn.edu/faculty-affairs/faculty-development-advancement-opportunities/grant-writing

Faculty publish

Arbefeville S, Thonen-Kerr E, Ferrieri P. Prospective and Retrospective Evaluation of the Performance of the FDA-Approved Cepheid Xpert Flu/RSV XC Assay. Lab Med. 2017 Sep 29. doi: 10.1093/labmed/lmx038. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/29036487#

Barnes AMT, Crespo-Diaz RJ, Cohenour J, Kirsch JD, Arbefeville S, Ferrieri P. A Noninvasive Rhizopus Infection With a Bladder Fungal Ball in a Patient With Poorly Controlled Diabetes Mellitus. Lab Med. 2017 Oct 23. doi: 10.1093/labmed/lmx060. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/29069422#

Upcoming events of interest

  • MPG members: Quarterly Luncheon meeting is scheduled for this Thursday, November 9 at noon in the Dale Shepard Room.  RSVP on your Google Calendar.
  • LMP Research Forum is Thursday, November 9 at 5:00 pm in the Dale Shepard Room at the Campus Club.  We start to review the preproposals for 2018 Innovation Grants.  Up first are Pawel Mroz/Bharat Thyagarajan and Elizabeth Courville/Nathan Pankratz.
  • All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop Path to Publication on how to write for peer-reviewed journals.  This fall’s workshop takes place on December 11 from 12:30 – 4:30 pm in the McNamara Alumni Center (right across Washington Avenue).  Here is the link to register: https://goo.gl/ktg6Ns  

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Funding Opportunities:  https://www.pathology.umn.edu/research/funding-opportunities

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, November 6, 2017

LMP News, October 23, 2017

Killeen named Ellis S. Benson Professor

Tony Killeen’s appointment to the Ellis S. Benson Professorship in Laboratory Medicine was recently approved by Dean Jackson.  Killeen, professor and vice-chair, succeeds John Eckfeldt who retired in September.  This professorship is named after Ellis Benson, the first department head of the merged departments of Laboratory Medicine and Pathology (1974 – 1989).  

Flanagan honored with platform presentation

Maggie Flanagan’s abstract was one of four selected for a full platform presentation and poster at the National Alzheimer’s Disease Center meeting in San Diego last week.  The title of both is: Administrative supplementOpportunity for neuropathology career development "Working towards the application of new imaging technologies in Alzheimer’s Disease and dementia research settings.”  

Skubitz speaks in Duluth

Amy Skubitz was the keynote scientific speaker at the Minnesota Ovarian Cancer Alliance's “Light Duluth Teal” Gala event held in September at the Duluth Entertainment Convention Center.  

Grzywacz awarded NIH Child Health/Human Development contract

Bartosz Grzywacz is PI on a NIH contract for a liver tissue and cell distribution system (LTCDS) awarded at the end of September for $367,158. This contract supports basic research in a variety of end-stage liver diseases by procuring, isolating, purifying, preserving, and delivering human liver tissue and hepatocytes, suitable for cellular and molecular studies, to qualified scientific investigators.  

Killeen visits the Far East

Tony Killeen was an invited speaker last Friday at the Korean Society for Laboratory Medicine in Seoul. The topic of his talk was "Proficiency testing: state of the art.”

Faculty meeting scheduled this Wednesday on fringe benefits

There is a faculty meeting this Wednesday after Grand Rounds (9:00 am), across the street at 2-101 Hasselmo Hall. We’ll have representatives from both the U and UMP benefits departments to answer any questions you may have on the new Roth 401k option available through UMP and on disability coverage from the University and UMP. 

Step up to interview residents 

It’s resident interview season.  Please volunteer to spend some time interviewing candidates.  Your experience with your own training and as a faculty member in our department are important “selling” points for candidates looking at the University of Minnesota.  Upcoming interview days are October 30, November 10, 13, December 4, 8, 18 and January 8.  Please let Maggie McGough know you’d be happy to interview at truax031@umn.edu

Complete your engagement survey

You received numerous emails over the past two weeks alerting you to complete the Employee Engagement Survey.  The survey will be open from October 16 to November 3.  The e-mail is from UofMNSurvey@us.confirmit.com.  It should take about 10 minutes or less to finish.   

Faculty publish

Spratt JR, Racila E, Shumway SJ. Acute interstitial pneumonitis requiring extracorporeal membrane oxygenation and lung transplantation in an adolescent patient. J Thorac Cardiovasc Surg. 2017 Aug 24. pii: S0022-5223(17)31788-9. doi: 10.1016/j.jtcvs.2017.08.027. [Epub ahead of print] http://www.jtcvsonline.org/article/S0022-5223(17)31788-9/fulltext

Boylan  KLM, Geschwind K, Koopmeiners JS, Geller MA, Starr T., and Skubitz APN.  A multiplex platform for the identification of ovarian cancer biomarkers. Clinical Proteomics (2017) 14:34. http://rdcu.be/wDoR

Latimer CS, Flanagan ME, Cimino PJ, Jayadev S, Davis M,Hoffer ZS, Montine TJ, Gonzalez-Cuyar LF, Bird TD, Keene CD. Neuropathological Comparison of Adult Onset and Juvenile Huntington's Disease with Cerebellar Atrophy: A Report of a Father and Son.  Huntingtons Dis. 2017 Oct 11. Doi:10:3233/JHD-170261 (Epub ahead of print). https://content.iospress.com/articles/journal-of-huntingtons-disease/jhd170261

Upcoming events of interest:

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, October 23, 2017

LMP News, October 10, 2017

LMP faculty land contracts

Mike Tsai was recently awarded three NIH contracts all from the National Institute of Child Health/Human Development.  The first is a $1.6M contract for the measurement of biospecimens in the Effects of Aspirin in Gestation and Reproduction or EAGeR trial.  The second contract focuses on “the development for maternal immune activity during pregnancy and offspring neurodevelopment for $501,569.”  The third is a contract for $171,697 on “genotyping performance of DNA from stored serum: a pilot study in the collaborative perinatal project.” Bharat Thyagarajan also received a contract for $149,750 from the NIH for a Study of Latinos (SOL) Ancillary H. Pylori Study.   

Phased retirement is now a two year program

Effective October 1, the Medical School has shortened the maximum length for phased retirement from five years to two years.  The Dean will consider an exception of up to three years in cases with a compelling need for additional time.  Phased retirement is a program provided to tenured faculty members who have an appointment of at least 75 percent and will be at least 55 years of age on their last day of employment. 

Do you have questions on disability or UMP’s Roth IRA or other fringe benefits?

We intend to schedule a faculty meeting later this month and have representatives from both the U and UMP to answer any questions you may have on the new Roth 401k option available through UMP and on disability coverage from the University or UMP.  Please send us any questions you might have so we can have the presentators prepare appropriately.  Send to Linda Kenny at kenny001@umn.edu.

Pickard presents poster at AAPA

Meghan Pickard, pathologists’ assistant, presented a poster on “Grossing photo database: a PA implemented storage solution” at the fall conference of the American Association of Pathologists Assistants (AAPA) in San Antonio.  Pickard did double duty at the conference and moderated a panel entitled “Article writing and mentorship.”  

Balfour on TV 

Hank Balfour was featured on KSTP news on September 29 featuring his labs’ work on an EPV vaccine.  In the feature Balfour said he hopes to start clinical trials as early as the fall of 2018.  http://kstp.com/medical/university-of-minnesota-mononucleosis-mono-vaccine/4616480/?cat=12196

Engagement survey opens in October

It’s been a while but this fall the University will ask faculty and staff to complete an Employee Engagement Survey.  The survey will be open from October 16 to November 3.  You will receive an email from Korn Ferry Hay Group with a link to the survey.  President Kaler says it will take 10 minutes to complete.  Data from the survey helps the University and its departments ensure that the U is a great place to work.

Faculty publish

Danni Li, Angela Radulescu, Rupendra T. Shrestha, Matthew Root, Amy B. Karger, Anthony A. Killeen, James S. Hodges, Shu-Ling Fan, Angela Ferguson, Uttam Garg, Lori J. Sokoll, Lynn A. Burmeister.  Association of biotin ingestion with performance of hormone and nonhormone assays in healthy adults. JAMA 2017.;318(12):1150-1160.doi:10.1001/jama.2017.13705.  https://goo.gl/yeqStZ  There is also a medical school report on this article at https://www.med.umn.edu/news-events/ingesting-biotin-large-doses-can-interfere-lab-tests-jama-study-shows

Song MGlasgow MMurugan PRivard C. Aggressive Angiomyxoma of the Vulva and Bladder. Obstet Gynecol. 2017 Sep 5. [Epub ahead of print] DOI: 10.1097/AOG.0000000000002254 https://insights.ovid.com/pubmed?pmid=28885430

Cao J, Steffen BT, Guan W, Budoff M, Michos ED, Kizer JR, Post WS, Tsai MY. Evaluation of Lipoprotein(a) Electrophoretic and Immunoassay Methods in Discriminating Risk of Calcific Aortic Valve Disease and Incident Coronary Heart Disease: The Multi-Ethnic Study of Atherosclerosis. Clin Chem 2017 [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28826575

Steffen BT, Guan W, Remaley AT, Stein JH, Tattersall MC, Kaufman J, Tsai MY. Apolipoprotein B is associated with carotid atherosclerosis progression independent of individual cholesterol measures in a 9-year prospective study of Multi-Ethnic Study of Atherosclerosis participants. J Clin Lipidol 2017 [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28826575

Reminders:

  • First Research Forum is scheduled for THIS Thursday, October 12 at 5:00 pm in the Dale Shephard room of the Campus Club.  Harry Orr will discuss “SCA1-from Basic Research to Therapeutic Development”
  • Steven Hecht, LMP, and Dorothy Hatsukami are the 2017 Dean's Distinguished Research Lectureship awardees. The event to honor them is October 26, 2017, from 4:30 – 7:00 at the Best Buy Theatre in Northrup Auditorium.  RSVP here:  https://www.med.umn.edu/DDRL2017
  • Last reminder to donate to Chainbreaker by October 13  https://chainbreakerride.org/ or make a check donation (with the full name of the rider in the memo line) to CHAINBREAKER, PO Box 14469, St. Paul, MN 55114
  • All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop on how to write for peer-reviewed journals.  This fall’s workshop takes place on December 11 from 12:30 – 4:30 pm in the McNamara Alumni Center (right across Washington Avenue).  Here is the link to register: https://goo.gl/ktg6Ns

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Tuesday, October 10, 2017

LMP News, September 25, 2017

Shimizu takes on new challenge

Yoji Shimizu started his appointment as director of the Graduate School’s Diversity Office this spring.  The Minnesota Daily did a story on Shimizu’s plans for the new position last week. http://www.mndaily.com/article/2017/09/graduate-school-hires-dean-to-refocus-efforts-on-diversity

Innovation Initiative pre-proposals are due October 1

Don’t forget that pre-proposals for the fourth round of innovation initiative grants are due on October 1.  These should be short (no more than a page please) and include the central idea, innovation, Team (PI and collaborators, approach and anticipated deliverables.  E-mail to Linda Kenny at kenny001@umn.edu.  For more information:  https://sites.google.com/a/umn.edu/lmp/innovation-initiatives

New pathologists’ assistant starts today

Kathleen Czmut, most recently at the Cleveland Clinic, joins our team of PAs in the Division of Anatomic Pathology today.  Czmut is a 2016 graduate of the Rosalind Franklin University of Medicine and Science with a MS in Pathologists’ Assistant. 

Path to Publication workshop is December 11

All assistant professors or any other faculty are encouraged to attend this half-day, interactive workshop on how to write for peer-reviewed journals.  This fall’s workshop takes place on December 11 from 12:30 – 4:30 pm in the McNamara Alumni Center (right across Washington Avenue).  Here is the link to register: https://goo.gl/ktg6Ns 

Biking season is not over yet!

Did you know there are 1500 miles of bike trails in Minnesota?  Many are right here in the metro but there are many rail to trail opportunities just an hour or so from the Twin Cities.  Check out

http://www.startribune.com/bike-trails-in-the-land-of-10-000-lakes/385106741/  

Heads up for new human subjects training requirement for PIs and research staff

Effective July 1, biomedical principal investigators, researchers, and study personnel must complete the newly organized and revised Collaborative Institutional Training Initiative (CITI) course, “Good Clinical Practice (GCP) and Human Research Protections for Biomedical Study Teams—Basic Course.” The training consists of 19 modules plus two elective modules and we’ve heard from a good source that it takes several hours to complete. The new hybrid GCP course is required for new studies submitted to the IRB. Also, once existing medical studies migrate to ETHOS, the training must be completed as part of the validation submission. https://research.umn.edu/units/irb/ethos/migration-plan 

Fifth Bioinformatician added to LMP Research Informatics Solutions (RIS) Team

Two new staff, Sarah Munroe and Todd Knutson, joined our clinical and research bioinformatics RIS team recently. This increases our LMP team to five bioinformaticians.  If you need bioinformatics help, we have a process.  You need to complete one-page request that outlines:  1) the scientific problem and its relevance to human health, 2) datasets that have been (or will be) generated, 3) specific bioinformatics support needs, 4) optimal time frame for support to be available (e.g. immediately, within a month, in 6 months, etc.), 5) a publication plan for the finalized datasets and/or 6) a plan for leveraging finalized datasets to procure external funding.  Requests will be accepted and reviewed on an ongoing basis pending availability of departmental support.  Send requests to Jean Kurata at jkurata@umn.edu. We have a committee (Scott Dehm, Harry Orr, Betsy Hirsch and Bharat Thyagarajan) that reviews and approves requests for bioinformatics time

Check out updates from the Dean’s office

  • President Kaler announced the continuation of system-wide strategic planning that includes Medicine and Health as one of five focus areas.  Dean Jackson will lead this focus area and looks forward to collaborating with faculty while doing so.
  • Finalists for the UMP CEO and Vice Dean for Clinical Affairs will be visiting campus this week.

Faculty publish

Cannon CM, Trembley JH, Kren BT, Unger GM, O’Sullivan MG, Cornax I, Modiano JF, Ahmed K: Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats. Am J Vet Res 78: 946–955, 2017. https://www.ncbi.nlm.nih.gov/pubmed/28738012

Verghese PS, Schmeling DO, Grimm JM, Filtz EA, Matas AJ, Balfour HH Jr. Transplantation of solid organ recipients shedding Epstein-Barr virus DNA pretransplant: a prospective study. Clin Transplant 2017. DOI: 10.1111/ctr.13116 https://www.ncbi.nlm.nih.gov/pubmed/28915342

Turk K, Flanagan ME, Josephson S, Keene CD, Jayadev S. Psychosis in spinocerebellar ataxias: a case series and study of Tyrosine Hydroxylase in substantia nigra. The Cerebellum. 2017 Sept; 1-9. doi: 10.1007s12311-017-0882-5  https://link.springer.com/article/10.1007/s12311-017-0882-5

Bharadwaj R, Cimino PJ, Flanagan ME, Latimer CS, Gonzalez-Cuyar LF, Juric-Sekhar G, Montine TJ, Marshall DA, Keene CD.  Application of the Condensed Protocol for the nIA-AA guidelines for the neuropathologic assessment of Alzheimer’s disease in an academic clinical practice. Histopathology 2017 Aug; doi:10.1111/his.13345 http://onlinelibrary.wiley.com/doi/10.1111/his.13345/full

Gauer JL, Jackson JB.  Association between the Medical College Admission Test scores and Alpha Omega Alpha Medical Honors Society membership. Advances in Medical Education and Practice. 2017:8, 627-632 https://goo.gl/6GpUFN

Whelton SP, Meeusen JW, Donato LJ, Jaffe AS, Saenger A, Sokoll LJ, Blumenthal RS, Jones SR, Martin SS.  Evaluating the atherogenic burden of individuals with a Friedewald-estimated low-density lipoprotein cholesterol <70 mg/dL compared with a novel low-density lipoprotein estimation method. J Clin Lipidol. 2017 Jul - Aug;11(4):1065-1072. doi: 10.1016/j.jacl.2017.05.005. Epub 2017 Jun 1.  Note:  This study was part of collaboration between Johns Hopkins, Mayo and the NHANES lipid data (of which ARDL is the NHANES lipid lab).  https://www.ncbi.nlm.nih.gov/pubmed/28826567

Reminders:

  • First Research Forum is scheduled for Thursday, October 12 at 5:00 pm in the Dale Shephard room of the Campus Club.  Harry Orr will discuss “From Basic Research to Therapeutic Development”
  • Steven Hecht, LMP, and Dorothy Hatsukami are the 2017 Dean's Distinguished Research Lectureship awardees. The event to honor them is October 26, 2017, from 4:30 – 7:00 at the Best Buy Theatre in Northrup Auditorium.  RSVP here:  https://www.med.umn.edu/DDRL2017
  • You can still donate to Chainbreaker until October 13  https://chainbreakerride.org/ or make a check donation (with the full name of the rider in the memo line) to CHAINBREAKER, PO Box 14469, St. Paul, MN 55114

 

LMP website: http://www.pathology.umn.edu/ 

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Publication date: 
Monday, September 25, 2017

LMP News, September 11, 2017

Killeen and ARDL are recipients of SPRINT ASK grant

Tony Killeen is the PI on a $309,999 SPRINT ancillary study award, which is a follow-up study to the SPRINT blood pressure hypertension trial. SPRINT ASK will follow SPRINT participants for a further year to examine the long term benefits and risks of lowering blood pressure.  ARDL continues to be a reference laboratory for this work.  

A SPRINT paper was published recently in the New England Journal of Medicine http://www.nejm.org/doi/full/10.1056/NEJMoa1611179  that looks at patient satisfaction and found no difference between lower and higher blood pressure. This answered the question about whether lower blood pressure, especially in older people, would cause more light-headedness and falls. The good news is that those concerns appear not to be a real problem.

Jackson elected to chair of UMP Board of Directors

In case you didn’t see the announcement on Friday, Brooks Jackson will be the new chair of the UMP Board of Directors effective October 1.  Jackson is Dean and also a faculty member in LMP.  

Two new faculty members arrive 

Alessio Giubellino joined our dermatopathology service on August 31.  He will also be doing research in the Masonic Cancer Center.  His office is C516 Mayo, 612-624-5407, pager is 899-9482, e-mail is agiubell@umn.edu.  Dorraya El-Ashry started September 5 and is a joint hire with the Masonic Cancer Center.  El-Ashry’s research will be focused in cancer biology and circulating cells in cancer.   Her research office and lab are located in 3-312 CCRB.  She doesn’t have a phone yet but her e-mail is delashry@umn.edu.

Emeritus Professor Andreas Rosenberg dies at 92

When Ellis Benson, the first head of a combined Department of Laboratory Medicine and Pathology, recruited the department’s initial core of basic science researchers, Andreas Rosenberg was one of his first hires.  Rosenberg was a biochemist, born in Estonia, escaped during WWII to Finland, and earned his PhD and DSci in Biochemistry from the University of Uppsala in Sweden.  He became part of a large NIH funded Hemoglobin Red-Cell Program project that included PIs from the Departments of LMP, Chemistry, Medicine and the University of Puerto Rico.  Rosenberg was also interested in the arts, notably the Guthrie Theatre and the Minneapolis Institute of Art.   He passed away on August 29.  The department plans to make a memorial in his memory to the Elizabeth and Andreas Rosenberg Theatre Scholarship at the University of Minnesota. (photo attached below). 

Balfour cited in U.S. News & World Report

A recent story in U.S. News highlights evidence that there may be a link between mononucleosis and multiple sclerosis among whites, blacks and Hispanics.  Hank Balfour, who is doing research in this area, was quoted saying that this research “strengthens the rationale for vaccine to prevent mono, because those who have had mono cannot protect themselves against MS.”  http://health.usnews.com/health-care/articles/2017-08-30/more-evidence-links-the-mono-virus-to-ms-risk 

Check out updates from the Dean’s office

  • Discussion continues with Fairview Health Services regarding the future of our MHealth partnership.  Progress is being made in defining what we need to be a top ranked Medical School and health system.  
  • Discussions continue with Children’s Minnesota to put detail about the structure governance and funds flow of a pediatric academic health system.
  • Three candidates were on campus to present their vision for the position of Associate Dean of Faculty Affairs.  
  • The search committee for the UMP CEO/Vice Dean for Clinical Affairs met last week to consider candidates presented by the search firm.

Faculty publish

Arbefeville S, Harris A, Ferrieri P. Comparison of sequencing the D2 region of the large subunit ribosomal RNA gene (MicroSEQ®) versus the internal transcribed spacer (ITS) regions using two public databases for identification of common and uncommon clinically relevant fungal species. J Microbiol Methods.2017Sep;140:40-46.doi:10.1016/j.mimet.2017.06.015.Epub2017Jun21. http://www.sciencedirect.com/science/article/pii/S0167701217301653

Reminders:

  • You can still donate to Chainbreaker until October 13  https://chainbreakerride.org/ or make a check donation (with the full name of the rider in the memo line) to CHAINBREAKER, PO Box 14469, St. Paul, MN 55114. 
  • LMP will offer its fourth round of Innovation Initiative grants for funding in 2018.  The due date for pre-proposals is October 1 with funding to start July 1, 2018.  See our google site (below) for complete information.
  • Grand Rounds are back on Wednesdays at 8:00 am in 450 MCRB (Masonic Cancer Research Building)
  • First Research Forum is scheduled for Thursday, October 12 at 5:00 pm in the Dale Shephard room of the Campus Club.  Harry Orr will discuss “From Basic Research to Therapeutic Development”

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

Andreas Rosenberg

 

 

 

 

Publication date: 
Monday, September 11, 2017

LMP News, August 28, 2017

We remember Jill Friedrich

On Thursday August 17th the Division of Molecular Pathology lost a highly skilled researcher.  Jill Friedrich died shortly after being hit by a vehicle while biking to a Minneapolis homeless shelter to run with its residents as part of the Mile in My Shoes program.  Friedrich worked as a molecular biologist in the Orr group on an oligonucleotide based therapy for a lethal neurodegenerative disease. In addition to her molecular biology skills, she was an accomplished artist contributing to figures in many papers and presentations. Jill leaves behind her mother Jayne, father Peter, brother Jake, and husband Jared.  Friedrich embraced life head on and will be deeply missed by her many colleagues, friends and family members.  A celebration of her life was held on Tuesday, August 22.  

Round IV of Innovation Initiatives kicks off 

LMP will offer its fourth round of Innovation Initiative grants for funding in 2018.  The due date for pre-proposals is October 1 with funding to start July 1, 2018. The format of the program will be the same as last year; pre-proposals will be presented at Research Forums during fall semester.  Full proposals will be due March 1, 2018.  See https://sites.google.com/a/umn.edu/lmp/innovation-initiatives for more information.  Flyer is also attached.  

Bell is official

Robert “Rob” Bell started his position in neuropathology on Monday, August 21.  An assistant professor, Bell will be on the neuropathology service with Brent Clark and Maggie Flanagan as well as be an active researcher with a lab in 326 Lions Research Building.  He and Flanagan are sharing a clinical office in C514-1 Mayo; phone 612-624-6563.  

LMP considers ban on sports

After three faculty members reported to work with broken extremities in the last few weeks due to extreme sports competition (softball, bicycle and hockey), the LMP faculty executive committee is considering whether faculty should be banned from participating in sports all together.  Being a couch potato may be considered a safer past time than actual team related activities. We are also seeking bids for human bubble wrapping services in the event that people still want to do sports.  Riding for Chainbreaker is exempt.

Check out these demographics for the Medical School Class of 2017

  • 61 different undergraduate institutions
  • 48 different majors
  • 34% are racially or ethnically diverse
  • 35 have already published
  • 28 were collegiate athletes
  • 19% are first generation college students
  • 13 different countries of origin
  • 6 served in the armed forces 

Flanagan speaks at symposium

Maggie Flanagan was an invited speaker last week at the Annual Adult Changes in Thought (ACT) study research symposium in Seattle.  The symposium brings together aging and dementia researchers from Kaiser Permanente Washington, the University of Washington and other collaborating institutions.  Flanagan presented an overview of her paper on analgesics, dementia and neuropathology.

Read updates from the Dean’s office

  • Compensation survey results will be presented to the clinical chiefs on August 29.
  • Negotiations continue with Children’s and Fairview. The Dean’s goal is have a clinical enterprise that promotes destination clinical care and a strong academic mission led by faculty.   

Don’t miss this week’s event

John Eckfeldt’s retirement reception is scheduled for Wednesday, August 30 at 4:00 pm on the Campus Club Terrace in Coffman Union.  Faculty, please RSVP to Jean Kurata at jkurata@umn.edu

Faculty publish

Shahi M, Dolan MMurugan P. Hyalinizing Clear Cell Carcinoma of the Bronchus. Head Neck Pathol. 2017 May 16. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28508996 

Stein T, Murugan P, Li F, El-Hag M. Can Medullary Carcinoma Arise in Thyroglossal Duct Cysts? A search for Parafollicular C-cells in 41 Resected Cases. Head Neck Pathol. 2017 May 23. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28536894

You can still donate to Chainbreaker until October 13

There were over one thousand riders in the inaugural Chainbreaker event and to date over $1M in funds have been raised.  You can still donate on line at https://chainbreakerride.org/ or make a check donation (with the full name of the rider in the memo line) to CHAINBREAKER, PO Box 14469, St. Paul, MN 55114.  Our riders included: Scott Dehm, Bartosz Grzywacz, Yoji Shimizu, Brooks Jackson, Kaylee Schwertfeger, Christopher Pennell, Michael Farrar, and Tucker LeBien.  

 

LMP website: http://www.pathology.umn.edu/  

LMP faculty google site: https://sites.google.com/a/umn.edu/lmp/

Grand Rounds videos: https://www.youtube.com/channel/UCHSc0zfvq6SUnNvDQI6oLwA

 

File innovation_initiatives_phase_iv_2017.docx

Publication date: 
Monday, August 28, 2017

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