Elizabeth Courville, MD

Assistant Professor, Department of Laboratory Medicine and Pathology

Elizabeth Courville

Contact Info

ecourvil@umn.edu

Office Phone 612-273-6054

Mailing Address:
MMC 609 Mayo
420 Delaware St SE
Minneapolis, MN 55455

Assistant Professor, Department of Laboratory Medicine and Pathology


Pathologist


Dartmouth Medical School, 2008

Massachusetts General Hospital, Boston, MA (Anatomic and Clinical Pathology), 2008-2012

Massachusetts General Hospital, Boston, MA (Tracy B. Mallory Clinical Fellow in Hematopathology), 2012-2013

Dartmouth Medical School (Pathology Post-Sophomore Fellowship), 2006-2007

Ohio University, Athens, OH (Chemistry/Biology), 1998-2002

Summary

Dr. Courville performs clinical translational research in the area of hematologic malignancies, including both myeloid and lymphoid malignancies. She is interested in the refinement of diagnostic categories, the evaluation of prognostic markers/features, and early detection of relapse. Current projects include morphologic evaluation of bone marrow biopsies after transplant for myelodysplastic syndromes, morphologic evaluation of bone marrow biopsies after NK cell therapy, and evaluation of immunohistochemical markers in post-transplant lymphoproliferative disorders (PTLD).

Professional Associations

  • United States and Canadian Academy of Pathology (USCAP)
  • College of American Pathologists (CAP)
  • American Society of Hematology (ASH)

Research

Publications

Selected Publications

  • Courville EL, Yohe S, Chou D, Nardi V, Lazaryan A, Thakral B, Nelson AC, Ferry JA, Sohani AR. EBV-negative monomorphic B-cell post-transplant lymphoproliferative disorders are pathologically distinct from EBV-positive cases and frequently contain TP53 mutations. Mod Pathol. 2016 Oct;29(10):1200-11. doi: 10.1038/modpathol.2016.130.
  • Ustun, C., Courville, E. L., DeFor, T., Dolan, M., Randall, N., Yohe, S., Bejanyan, N., Warlick, E., Brunstein, C., Weisdorf, D. J., Linden, M. A. Myeloablative, but not Reduced-Intensity, Conditioning Overcomes the Negative Effect of Flow-Cytometric Evidence of Leukemia in Acute Myeloid Leukemia. Biology of Blood and Marrow Transplantation. 2016; 22(4):669-675.
  • Ustun C, Courville EL. Resolution of osteosclerosis after alloHCT in systemic mastocytosis. Blood. 2016 Apr 7; 127(14):1836.
  • Moench L, Sachs Z, Aasen G, Dolan M, Dayton V, Courville EL. Double- and triple-hit lymphomas can present with features suggestive of immaturity, including TdT expression, and create diagnostic challenges. Leuk Lymphoma.2016 Feb 18:1-10 [Epub ahead of print]
  • Ustun C, Smith A, Cayci Z, Courville EL, Corbacioglu S, Akin C, Horny HP, Valent P, Devine S, Weisdorf DJ. Allogeneic hematopoietic cell transplantation in systemic mastocytosis: is there a high risk for veno-occlusive disease? Eur J Haematol.2016 Jun; 96(6):655-7.
  • Courville EL*, Singh C*, Yohe S, Linden MA, Naemi K, Berger M, Ustun C, McKenna R, Dolan M. Patients with a history of prior chemotherapy and isolated del(20q) with minimal myelodysplasia have an indolent course. *co-first authors. Am J Clinical Pathol.2016 Apr; 145(4):459-66.
  • Courville EL, Sohani AR, Hasserjian RP, Zukerberg LR, Harris NL, Ferry JA. Diverse clinicopathologic features in human herpesvirus 8-associated lymphomas lead to diagnostic problems. Am J Clin Pathol. 2014 Dec: 142(6):816-29.
  • Üstün, Celalettin; Cayci, Zuzan; Courville, Elizabeth L. A patient with skin lesions, osteosclerosis and hepatosplenomegaly. Br J Haematol. 2014 Nov; 167(3) 291
  • Thakral B, Courville E. Crystal-storing histiocytosis with IgD kappa-associated plasma cell neoplasm. Blood. 2014 Jun 5; 123(23):3540.Liegel J., Courville E, Sachs Z., Ustun C. Use of sorafenib for post-transplant relapse in FLT3/ITD-positive acute myelogenous leukemia: maturation induction and cytotoxic effect. Haematologica 2014 Nov; 99(11):e222-4.

National Presentations

  • March 2012 "Acute myeloid leukemia arising from chronic myelomonocytic leukemia has poor prognosis and high incidence of normal karyotype and NPM1 mutation" (Poster), Courville EL, Wu Y, Kourda J, Roth CG, Brockmann J, de Leval L, Orazi A, Hasserjian, R. United States and Canadian Academy of Pathology, 101st Annual Meeting, Vancouver, BC, Canada. Modern Pathol 2012:25:331A.
  • March 2011 "Retrospective review of tonsil specimens: experiential assessment of a clinical practice" (Poster), Courville EL, Lew M, Sadow, PM. United States and Canadian Academy of Pathology, 100th Annual Meeting, San Antonio, TX, Modern Pathol 2011:24:277A.
  • March 2011 "MGMT (O6-MethylguanineDNA Methyltransferase) is inactivated in a significant subset of distal esophageal adenocarcinomas: implications for neoadjuvant chemoradiation therapy" (Poster), Lisovsky M, Mino-Kenudson M, Lefferts J, Courville E, Zaki B, Calvo LN, Hong TS, Tsongalis GJ, Lauwers GY, Srivastava A. United states and Canadian Academy of Pathology, 100th Annual Meeting, San Antonia, TX, Modern Pathol 2011:24 157A.
  • March 2010 "Lack of ERCC1 and Olfactomedin 4 (Olfm4) protein expression predicts neoadjuvant therapy sensitivity in GE junction adenocarcinoma (GEJAd)" (Poster), Courville EL, Srivastava A, Hong TS, Calvo LN, Zaki BI, Mino-Kenudson M. United States and Canadian Academy of Pathology, 99th Annual Meeting, 2010, Washington, DC, Modern Pathol 2010:23:141A.
  • March 2008 "Isolated asymptomatic ileitis does not progress to Crohn's disease despite presence of features of chronicity in ileal biopsies" (Poster), Fingar EL, Vay T, Wilcox AR, Siegel C, Suriawinata AA, Srivastava A. United States and Canadian Academy of Pathology, 97th Annual Meeting, 2008, Denver, Colorado. Modern Pathol 2008:21:118A. Runner-up for the best presentation by a resident in Gastrointestinal pathology by the Rodger C. Haggitt Gastrointestinal Pathology Society.

Clinical

Specialties

  • HematopathologyPathology

Board Certifications

Anatomic and Clinical Pathology (2012), Hematology (2013)