Paari Murugan, MD

Assistant Professor, Department of Laboratory Medicine and Pathology

Paari Murugan

Contact Info

pmurugan@umn.edu

Office Phone 612-273-5465

Lab Phone 612-273-1142

Mailing Address:
Surgical Pathology
MMC 76 Mayo
8076A (Campus Delivery Code)
420 Delaware St SE
Minneapolis, MN 55455

Jawaharlal Insititute of Post-Graduate Medical Education and Research, Pondicherry, India (Pathology), 2008

University of Oklahoma Health Sciences Center (Anatomic Pathology), 2012

MD Anderson Cancer Center (Oncological Surgical Pathology), 2013

Memorial Sloan Kettering Center (Genitourinary Pathology), 2014

MB, BS, Madras Medical College, Chennai, India, 2004

Summary

Dr. Murugan is a board certified anatomic pathologist whose area of expertise is in the surgical pathology of genitourinary and bone / soft tissue tumors. He works closely with multidisciplinary teams involving urologists, orthopedicians, medical/radiation oncologists, and radiologists in providing care to patients with kidney, urinary bIadder, prostate, adrenal, testis, bone and soft tissue neoplasms. His role involves establishing accurate tissue diagnosis on biopsies and surgical excisions, a critical component in guiding treatment decisions. 

In addition to his clinical diagnostic activities, Dr. Murugan is involved in medical student, resident and fellow education as well as translational research. His research projects mainly focus on the histomorphological features of neoplastic entities and their immunohistochemical and molecular profiles. He correlates these findings with tumor behavior in relevance to therapy and prognosis. He has published more than 30 peer reviewed journal articles and is currently working on several projects including studies addressing bladder cancer biomarkers, MRI guided prostate cancer detection, bladder cancer prognostication using cell cycle gene expression, radiation response in myxoid liposarcoma, low grade prostate cancer in African-American men and clinical markers of heterocyclic aromatic amines for human biomonitoring. He serves as peer-reviewer for several journals including Journal of Urology, BMC Cancer, Virchows Archiv and Human Pathology.

Research

Publications

Selected Publications

  • Shahi M, Dolan M, Murugan P. Hyalinizing Clear Cell Carcinoma of the Bronchus. Head Neck Pathol. 2017 May 16. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28508996
  • Stein T, Murugan P, Li F, El-Hag M. Can Medullary Carcinoma Arise in Thyroglossal Duct Cysts? A search for Parafollicular C-cells in 41 Resected Cases. Head Neck Pathol. 2017 May 23. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28536894
  • Murugan P, Rao P, Tamboli P, Czerniak B, Guo CC. Primary Ewing Sarcoma / Primitive Neuroectodermal Tumor of the Kidney: A Clinicopathologic Study of 23 Cases. Pathol Oncol Res. 2017 Apr 20. doi: 10.1007/s12253-017-0228-0. [Epub ahead of print] PubMed PMID: 28429277.
  • Mesa H, Gilles S, Datta MW, Murugan P, Larson W, Dachel S, Manivel JC. Comparative immunomorphology of testicular Sertoli and sertoliform tumors. Hum Pathol. 2017 Mar;61:181-189. doi: 10.1016/j.humpath.2016.11.004. Epub 2016 Dec 8. PubMed PMID: 27939779.
  • Xiao S, Guo J, Yun BH, Villalta PW, Krishna S, Tejpaul R, Murugan P, Weight CJ, Turesky RJ. Biomonitoring DNA Adducts of Cooked Meat Carcinogens in Human Prostate by Nano Liquid Chromatography-High Resolution Tandem Mass Spectrometry: Identification of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine DNA Adduct. Anal Chem. 2016 Dec 20;88(24):12508-12515. doi: 10.1021/acs.analchem.6b04157. Epub 2016 Dec 1. PubMed PMID: 28139123.
  • Fitzpatrick M, Pulver T, Klein M, Murugan P, Khalifa M, Amin K. Perivascular Epithelioid Cell Tumor of the Uterus with Ovarian Involvement: A Case Report and Review of the Literature. Am J Case Rep.2016 May 6;17:309-14.
  • Adibi M, Thomas AZ, Borregales LD, Merrill MM, Slack RS, Chen HC, Sircar K, Murugan P, Tamboli P, Jonasch E, Tannir NM, Matin SF, Wood CG, Karam JA.  Percentage of sarcomatoid component as a prognostic indicator for survival in renal cell carcinoma with sarcomatoid dedifferentiation. Urol Oncol. 2015 Oct;33(10):427.e17-23.
  • Singh RR, Murugan P, Patel LR, Voicu H, Yoo SY, Majewski T, Mehrotra M, Wani K, Tannir N, Karam JA, Jonasch E, Wood CG, Creighton CJ, Medeiros LJ, Broaddus RR, Tamboli P, Baggerly KA, Aldape KD, Czerniak B, Luthra R, Sircar K.Intratumoral morphologic and molecular heterogeneity of rhabdoid renal cell carcinoma:challenges for personalized therapy.  Mod Pathol. 2015 Sep;28(9):1225-35.
  • Murugan P, Stevenson ME, Hassell LA: Performance validation in anatomic pathology: successful integration of a new classification system into the practice setting using the updated lung non-small cell carcinoma recommendations. Arch Pathol Lab Med. 2014 Jan;138(1):105-9.
  • Fatani HA, Junco GD, Murugan P, El-Naggar AK. Ocular Non-pigmented Ciliary Adenomatous Neoplasm: Report of a Rare Case and Review of the Clinicopathologic Classification. Int J Ophthalmic Pathol 2014 3:1. doi:10.4172/2324-8599.1000131.
  • Devadoss CW, Murugan P, Basu D, Jagdish S: Lipoadenoma of the parotid gland: Report of a rare case. Journal of Clinical and Diagnostic Research 2012; 6(6):1076.
  • Nabbout P, Furr J, Murugan P, Slobodov G. Plasmacytoid urothelial carcinoma of the bladder metastatic to the stomach: A case report. Case Reports in Urology, vol. 2012, Article ID 715951, 4 pages, 2012.
  • Miller VL, Lin HK, Murugan P, Fan M, Penning TM, Brame LS, Yang Q, Fung KM Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma. Int J Clin Exp Pathol 2012;5(4) [Epub ahead of print].

Books

  • Gopal M, Murugan P, Mamdani N, Jayashree S, Gopichandran V: Acing the USMLE and the Match – A guide for international medical graduates. Jaypee Medical Publishers, New Delhi, 2008.

Clinical

Board Certifications

American Board of Pathology, 2012