First-Year Mono Study
Recruitment for the First-Year Mono Study concluded on October 27th. Our researchers would like to thank the 235 first year students at the University of Minnesota that participated in the First-Year Mono study. With the students' help, researchers are one step closer to developing a vaccine for EBV. Participants are expected to recieve results on their EBV status in the upcoming week.
Researchers partnered with Housing and Residental Life to recruit students for research study at Centennial Hall. The goal of this study was to test the sensitivity and specificity of an oral swab, a non-invasive method, to measure Epstein-Barr virus antibodies and viral load in students. If the oral swab is effective, this method can used as an alternative for needles in future studies involving children. The measurement of antibodies will be useful for determining the best age to vaccinate.
The manuscript for this study was submitted for publication in the Journal of Clinical Virology on June 29th, 2018.
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Evidence That Parents Could Be the Source of Primary EBV Infection for Young Children
Our study of EBV DNA in parental oral secretions as a potential source of primary infection for their young children has been accepted for publication in Clinical Infectious Diseases, the top-ranked, peer-reviewed infectious diseases medical journal. We found that 28% of parents with children younger than 8 years old had EBV in their oral secretions, and the prevalence of shedding was higher among non-whites, consistent with the observation that non-white children acquire EBV at a younger age than their white counterparts. We are especially proud that our research paper was accepted WITHOUT REVISIONS!
Impact of EBV
280,000 cases of mono in U.S college freshmen annually
200,000 new cases of EBV-associated cancers annually worldwide
2.3 million cases of multiple sclerosis worldwide